Reception and transmission of taste information in type ii and type ie taste bud cells

Ryusuke Yoshida, Mayu Niki, Yoshihiro Murata, Noriatsu Shigemura, Yuzo Ninomiya

Research output: Contribution to journalReview article

Abstract

Gustatory information processing begins with taste bud cells,astr which are activated by sapid molecules via specific taste receptors and transmit their signals to gustatory afferent fibers. Taste bud cells are morphologically classified into 4 groups (Type I -IV cells), two of which are involved in gustatory sig-naling. Type II cells express sweet, bitter, and umami taste receptors and transduction components and respond best to sweet, bitter, or umami stimuli, suggesting that sweet, bitter, and umami tastes are detected by different sets of Type II cells. Type m cells express putative sour taste receptors and respond to sour or multiple taste stimuli, indicating that sour tastes are mediated by Typem cells. These data suggest that each taste quality could be discriminated among taste bud cells. Type II cells do not possess a conventional synaptic structure but they release ATP in response to taste stimuli. Typem cells have a synaptic structure and they release serotonin and norepinephrine but not ATP. Therefore, each taste cell may use distinct mechanisms and transmitters for signal transmission to gustatory nerve fibers.

Original languageEnglish
Pages (from-to)358-364
Number of pages7
Journaljournal of oral biosciences
Volume52
Issue number4
DOIs
Publication statusPublished - Jan 1 2010

Fingerprint

Taste Buds
Adenosine Triphosphate
Fibers
Transmitters
Serotonin
Norepinephrine
Molecules
Automatic Data Processing
Nerve Fibers

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Dentistry(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Reception and transmission of taste information in type ii and type ie taste bud cells. / Yoshida, Ryusuke; Niki, Mayu; Murata, Yoshihiro; Shigemura, Noriatsu; Ninomiya, Yuzo.

In: journal of oral biosciences, Vol. 52, No. 4, 01.01.2010, p. 358-364.

Research output: Contribution to journalReview article

Yoshida, Ryusuke ; Niki, Mayu ; Murata, Yoshihiro ; Shigemura, Noriatsu ; Ninomiya, Yuzo. / Reception and transmission of taste information in type ii and type ie taste bud cells. In: journal of oral biosciences. 2010 ; Vol. 52, No. 4. pp. 358-364.
@article{af2061dcd4ce4c32bff4115b94fb22b4,
title = "Reception and transmission of taste information in type ii and type ie taste bud cells",
abstract = "Gustatory information processing begins with taste bud cells,astr which are activated by sapid molecules via specific taste receptors and transmit their signals to gustatory afferent fibers. Taste bud cells are morphologically classified into 4 groups (Type I -IV cells), two of which are involved in gustatory sig-naling. Type II cells express sweet, bitter, and umami taste receptors and transduction components and respond best to sweet, bitter, or umami stimuli, suggesting that sweet, bitter, and umami tastes are detected by different sets of Type II cells. Type m cells express putative sour taste receptors and respond to sour or multiple taste stimuli, indicating that sour tastes are mediated by Typem cells. These data suggest that each taste quality could be discriminated among taste bud cells. Type II cells do not possess a conventional synaptic structure but they release ATP in response to taste stimuli. Typem cells have a synaptic structure and they release serotonin and norepinephrine but not ATP. Therefore, each taste cell may use distinct mechanisms and transmitters for signal transmission to gustatory nerve fibers.",
author = "Ryusuke Yoshida and Mayu Niki and Yoshihiro Murata and Noriatsu Shigemura and Yuzo Ninomiya",
year = "2010",
month = "1",
day = "1",
doi = "10.2330/joralbiosci.52.358",
language = "English",
volume = "52",
pages = "358--364",
journal = "Journal of Oral Biosciences",
issn = "1349-0079",
publisher = "Japanese Association for Oral Biology",
number = "4",

}

TY - JOUR

T1 - Reception and transmission of taste information in type ii and type ie taste bud cells

AU - Yoshida, Ryusuke

AU - Niki, Mayu

AU - Murata, Yoshihiro

AU - Shigemura, Noriatsu

AU - Ninomiya, Yuzo

PY - 2010/1/1

Y1 - 2010/1/1

N2 - Gustatory information processing begins with taste bud cells,astr which are activated by sapid molecules via specific taste receptors and transmit their signals to gustatory afferent fibers. Taste bud cells are morphologically classified into 4 groups (Type I -IV cells), two of which are involved in gustatory sig-naling. Type II cells express sweet, bitter, and umami taste receptors and transduction components and respond best to sweet, bitter, or umami stimuli, suggesting that sweet, bitter, and umami tastes are detected by different sets of Type II cells. Type m cells express putative sour taste receptors and respond to sour or multiple taste stimuli, indicating that sour tastes are mediated by Typem cells. These data suggest that each taste quality could be discriminated among taste bud cells. Type II cells do not possess a conventional synaptic structure but they release ATP in response to taste stimuli. Typem cells have a synaptic structure and they release serotonin and norepinephrine but not ATP. Therefore, each taste cell may use distinct mechanisms and transmitters for signal transmission to gustatory nerve fibers.

AB - Gustatory information processing begins with taste bud cells,astr which are activated by sapid molecules via specific taste receptors and transmit their signals to gustatory afferent fibers. Taste bud cells are morphologically classified into 4 groups (Type I -IV cells), two of which are involved in gustatory sig-naling. Type II cells express sweet, bitter, and umami taste receptors and transduction components and respond best to sweet, bitter, or umami stimuli, suggesting that sweet, bitter, and umami tastes are detected by different sets of Type II cells. Type m cells express putative sour taste receptors and respond to sour or multiple taste stimuli, indicating that sour tastes are mediated by Typem cells. These data suggest that each taste quality could be discriminated among taste bud cells. Type II cells do not possess a conventional synaptic structure but they release ATP in response to taste stimuli. Typem cells have a synaptic structure and they release serotonin and norepinephrine but not ATP. Therefore, each taste cell may use distinct mechanisms and transmitters for signal transmission to gustatory nerve fibers.

UR - http://www.scopus.com/inward/record.url?scp=79952205906&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79952205906&partnerID=8YFLogxK

U2 - 10.2330/joralbiosci.52.358

DO - 10.2330/joralbiosci.52.358

M3 - Review article

VL - 52

SP - 358

EP - 364

JO - Journal of Oral Biosciences

JF - Journal of Oral Biosciences

SN - 1349-0079

IS - 4

ER -