Reconstruction of four-dimensional computed tomography images during treatment time using electronic portal imaging device images based on a dynamic 2D/3D registration

T. Nakamoto, Hidetaka Arimura, T. A. Hirose, Ohga Saiji, Y. Umezu, Y. Nakamura, Hiroshi Honda, Tomonari Sasaki

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The goal of our study was to develop a computational framework for reconstruction of four-dimensional computed tomography (4D-CT) images during treatment time using electronic portal imaging device (EPID) images based on a dynamic 2D/3D registration. The 4D-CT images during treatment time ("treatment" 4D-CT images) were reconstructed by performing an affine transformation-based dynamic 2D/3D registration between dynamic clinical portal dose images (PDIs) derived from the EPID images with planning CT images through planning PDIs for all frames. Elements of the affine transformation matrices (transformation parameters) were optimized using a Levenberg-Marquardt (LM) algorithm so that the planning PDIs could be similar to the dynamic clinical PDIs for all frames. Initial transformation parameters in each frame should be determined for finding optimum transformation parameters in the LM algorithm. In this study, the optimum transformation parameters in a frame employed as the initial transformation parameters for optimizing the transformation parameter in the consecutive frame. Gamma pass rates (3 mm/3%) were calculated for evaluating a similarity of the dose distributions between the dynamic clinical PDIs and "treatment" PDIs, which were calculated from "treatment" 4D-CT images, for all frames. The framework was applied to eight lung cancer patients who were treated with stereotactic body radiation therapy (SBRT). A mean of the average gamma pass rates between the dynamic clinical PDIs and the "treatment" PDIs for all frames was 98.3±1.2% for eight cases. In conclusion, the proposed framework makes it possible to dynamically monitor patients' movement during treatment time.

Original languageEnglish
Title of host publicationMedical Imaging 2017
Subtitle of host publicationPhysics of Medical Imaging
EditorsTaly Gilat Schmidt, Joseph Y. Lo, Thomas G. Flohr
PublisherSPIE
ISBN (Electronic)9781510607095
DOIs
Publication statusPublished - Jan 1 2017
EventMedical Imaging 2017: Physics of Medical Imaging - Orlando, United States
Duration: Feb 13 2017Feb 16 2017

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume10132
ISSN (Print)1605-7422

Other

OtherMedical Imaging 2017: Physics of Medical Imaging
CountryUnited States
CityOrlando
Period2/13/172/16/17

Fingerprint

Four-Dimensional Computed Tomography
Tomography
tomography
Imaging techniques
Equipment and Supplies
electronics
dosage
Therapeutics
Planning
planning
Lung Neoplasms
Radiotherapy

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Nakamoto, T., Arimura, H., Hirose, T. A., Saiji, O., Umezu, Y., Nakamura, Y., ... Sasaki, T. (2017). Reconstruction of four-dimensional computed tomography images during treatment time using electronic portal imaging device images based on a dynamic 2D/3D registration. In T. G. Schmidt, J. Y. Lo, & T. G. Flohr (Eds.), Medical Imaging 2017: Physics of Medical Imaging [101322V] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10132). SPIE. https://doi.org/10.1117/12.2254000

Reconstruction of four-dimensional computed tomography images during treatment time using electronic portal imaging device images based on a dynamic 2D/3D registration. / Nakamoto, T.; Arimura, Hidetaka; Hirose, T. A.; Saiji, Ohga; Umezu, Y.; Nakamura, Y.; Honda, Hiroshi; Sasaki, Tomonari.

Medical Imaging 2017: Physics of Medical Imaging. ed. / Taly Gilat Schmidt; Joseph Y. Lo; Thomas G. Flohr. SPIE, 2017. 101322V (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10132).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Nakamoto, T, Arimura, H, Hirose, TA, Saiji, O, Umezu, Y, Nakamura, Y, Honda, H & Sasaki, T 2017, Reconstruction of four-dimensional computed tomography images during treatment time using electronic portal imaging device images based on a dynamic 2D/3D registration. in TG Schmidt, JY Lo & TG Flohr (eds), Medical Imaging 2017: Physics of Medical Imaging., 101322V, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 10132, SPIE, Medical Imaging 2017: Physics of Medical Imaging, Orlando, United States, 2/13/17. https://doi.org/10.1117/12.2254000
Nakamoto T, Arimura H, Hirose TA, Saiji O, Umezu Y, Nakamura Y et al. Reconstruction of four-dimensional computed tomography images during treatment time using electronic portal imaging device images based on a dynamic 2D/3D registration. In Schmidt TG, Lo JY, Flohr TG, editors, Medical Imaging 2017: Physics of Medical Imaging. SPIE. 2017. 101322V. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). https://doi.org/10.1117/12.2254000
Nakamoto, T. ; Arimura, Hidetaka ; Hirose, T. A. ; Saiji, Ohga ; Umezu, Y. ; Nakamura, Y. ; Honda, Hiroshi ; Sasaki, Tomonari. / Reconstruction of four-dimensional computed tomography images during treatment time using electronic portal imaging device images based on a dynamic 2D/3D registration. Medical Imaging 2017: Physics of Medical Imaging. editor / Taly Gilat Schmidt ; Joseph Y. Lo ; Thomas G. Flohr. SPIE, 2017. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE).
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