Recurrence 11 years after complete response to gemcitabine, 5-fluorouracil, and cisplatin chemotherapy followed by radiotherapy in a patient with advanced pancreatic cancer: A case report

Tomoyuki Uchihara, Yo Ichi Yamashita, Wang Hualin, Kazuki Takeishi, Shinji Itoh, Norihumi Harimoto, Tomoharu Yoshizumi, Shinichi Aishima, Ken Shirabe, Hideo Baba, Yoshihiko Maehara

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Abstract

A 63-year-old man diagnosed with locally advanced pancreatic ductal adenocarcinoma (PDAC; stage IIa) was treated with chemotherapy (gemcitabine, 5-fluorouracil and cisplatin) followed by radiotherapy. He had complete response by imaging and relapse-free survival for 11 years. However, he subsequently presented with local tumor recurrence and underwent pancreaticoduodenectomy followed by chemotherapy; a partial response was achieved. As in liver metastasis of colonic cancer, complete response by imaging in PDAC may not mean pathological complete response. We would propose the importance of adjuvant surgery for a patient with PDAC with complete response by imaging after chemoradiotherapy.

Original languageEnglish
Pages (from-to)2867-2872
Number of pages6
JournalAnticancer research
Volume35
Issue number5
Publication statusPublished - May 1 2015

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

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