Recurrence of Takotsubo cardiomyopathy with coronary slow flow phenomenon

Tomotake Tokunou, Kenji Sadamatsu

Research output: Contribution to journalArticlepeer-review


This report presents the case of a 54-year-old female with Takotsubo cardiomyopathy that recurred 12 years after the first episode. The coronary angiography at the first admission revealed ergonovine-induced coronary vasoconstriction in the left coronary artery, and recurrence recurred after the interruption of vasodilator therapy to prevent vasospasm. In addition, the coronary angiography both in the first and second event demonstrated coronary slow flow phenomenon, which improved after the intracoronary administration of nicorandil. These findings indicate that coronary microvascular constriction plays an important role in the pathophysiology of Takotsubo cardiomyopathy.

Original languageEnglish
Pages (from-to)e100-e106
JournalJournal of Cardiology Cases
Issue number2
Publication statusPublished - Apr 2012

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

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