Reductive etherification under microfluidic conditions: Application to practical synthesis of the FGHIJ-ring system of yessotoxin

Tohru Oishi, Tomoyoshi Imaizumi, Michio Murata

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Reductive etherification, a key reaction for constructing the H-ring in the convergent synthesis of the FGHIJ-ring system of yessotoxin, was problematic because the yield dramatically decreased upon increasing the scale of the reaction. This issue was solved by the use of a microflow reactor, and a gram scale reaction was successfully performed.

Original languageEnglish
Pages (from-to)108-109
Number of pages2
JournalChemistry Letters
Volume39
Issue number2
DOIs
Publication statusPublished - 2010
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

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