Abstract
An asymmetric monoborylation of alkenylsilanes catalyzed by a copper(I) complex with the chiral bisphosphine ligand BenzP* is reported. The reaction proceeded with excellent regioselectivity and high enantioselectivity to afford the corresponding optically active organoboronate esters with a stereogenic C-B bond containing a vicinal silyl group. The synthetic utility of the product is demonstrated through stepwise transformations to multifunctional optically active compounds in a stereospecific manner.
| Original language | English |
|---|---|
| Pages (from-to) | 3527-3531 |
| Number of pages | 5 |
| Journal | Advanced Synthesis and Catalysis |
| Volume | 355 |
| Issue number | 18 |
| DOIs | |
| Publication status | Published - Dec 16 2013 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Catalysis
- Organic Chemistry
Cite this
Regio- and enantioselective monoborylation of alkenylsilanes catalyzed by an electron-donating chiral phosphine-Copper(I) complex. / Kubota, Koji; Yamamoto, Eiji; Ito, Hajime.
In: Advanced Synthesis and Catalysis, Vol. 355, No. 18, 16.12.2013, p. 3527-3531.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Regio- and enantioselective monoborylation of alkenylsilanes catalyzed by an electron-donating chiral phosphine-Copper(I) complex
AU - Kubota, Koji
AU - Yamamoto, Eiji
AU - Ito, Hajime
PY - 2013/12/16
Y1 - 2013/12/16
N2 - An asymmetric monoborylation of alkenylsilanes catalyzed by a copper(I) complex with the chiral bisphosphine ligand BenzP* is reported. The reaction proceeded with excellent regioselectivity and high enantioselectivity to afford the corresponding optically active organoboronate esters with a stereogenic C-B bond containing a vicinal silyl group. The synthetic utility of the product is demonstrated through stepwise transformations to multifunctional optically active compounds in a stereospecific manner.
AB - An asymmetric monoborylation of alkenylsilanes catalyzed by a copper(I) complex with the chiral bisphosphine ligand BenzP* is reported. The reaction proceeded with excellent regioselectivity and high enantioselectivity to afford the corresponding optically active organoboronate esters with a stereogenic C-B bond containing a vicinal silyl group. The synthetic utility of the product is demonstrated through stepwise transformations to multifunctional optically active compounds in a stereospecific manner.
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UR - http://www.scopus.com/inward/citedby.url?scp=84890793829&partnerID=8YFLogxK
U2 - 10.1002/adsc.201300765
DO - 10.1002/adsc.201300765
M3 - Article
VL - 355
SP - 3527
EP - 3531
JO - Advanced Synthesis and Catalysis
JF - Advanced Synthesis and Catalysis
SN - 1615-4150
IS - 18
ER -