Regio- and enantioselective monoborylation of alkenylsilanes catalyzed by an electron-donating chiral phosphine-Copper(I) complex

Koji Kubota, Eiji Yamamoto, Hajime Ito

Research output: Contribution to journalArticlepeer-review

30 Citations (Scopus)

Abstract

An asymmetric monoborylation of alkenylsilanes catalyzed by a copper(I) complex with the chiral bisphosphine ligand BenzP* is reported. The reaction proceeded with excellent regioselectivity and high enantioselectivity to afford the corresponding optically active organoboronate esters with a stereogenic C-B bond containing a vicinal silyl group. The synthetic utility of the product is demonstrated through stepwise transformations to multifunctional optically active compounds in a stereospecific manner.

Original languageEnglish
Pages (from-to)3527-3531
Number of pages5
JournalAdvanced Synthesis and Catalysis
Volume355
Issue number18
DOIs
Publication statusPublished - Dec 16 2013

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Organic Chemistry

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