Regio- and stereoselective synthesis of multisubstituted enamides by treatment of ynamides with boronic acids

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Abstract

Addition of boronic acids to ynamides can be a useful method to obtain enamides, which have been considered as good prochiral precursors for the synthesis of optically active compounds bearing quaternary stereogenic centers. Although the regioselectivity for carbometalation should be required, recently, highly regio- and stereocontrolled addition reactions have been developed by using transition metal catalysts. In this review, three types of regio- and stereocontrolled synthesis of multisubstituted enamides are discussed.

Original languageEnglish
Pages (from-to)749-750
Number of pages2
JournalYuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry
Volume73
Issue number7
DOIs
Publication statusPublished - Jan 1 2015

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Boronic Acids
Bearings (structural)
Regioselectivity
Addition reactions
Transition metals
Catalysts

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

Cite this

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