TY - JOUR
T1 - Regulation of Oocyte Growth and Maturation in Fish
AU - Nagahama, Yoshitaka
AU - Yoshikuni, Michiyasu
AU - Yamashita, Masakane
AU - Tokumoto, Toshinobu
AU - Katsu, Yoshinao
N1 - Funding Information:
The authors thank the many wonderful colleagues who have contributed to the work described herein, especially G. Young, M. Nakamura, H. Kagawa, S. Adachi, M. Tanaka, N. Sakai, T. Hirai, M. Matsuyama, M. Takahashi, H. Kajiura, and S. Fukada. A special thanks to N. Nagahama and K. Noda for their assistance in the preparation of this manuscript. This work was supported in part by a grant-in-aid from the Ministry of Education, Science, and Culture in Japan (02102010 to Y. N.).
PY - 1995/1/1
Y1 - 1995/1/1
N2 - This chapter discusses the current status of the investigations on the hormonal regulation of oocyte growth and maturation in fish. Pituitary gonadotropins are of primary importance in triggering these processes in fish oocytes. In both cases, however, the actions of gonadotropins are not direct but are mediated by the follicular production of steroidal mediators, estradiol-17β (oocyte growth), and 17α,20β-dihydroxy-4-pregnene-3-one (DP) or 4-pregnen-17,20β,21-triol-3-one (20β-S) (oocyte maturation). It has been established that both estradiol- 17β and 17α,20β-DP are biosynthesized by salmonid ovarian follicles through an interaction of two cell layers—namely, the thecal and the granulosa cell layers (two-cell-type model). The granulosa cell layers are the sites of production of these two steroidal mediators, but their production depends on the provision of the precursor steroids by the thecal cell layers.
AB - This chapter discusses the current status of the investigations on the hormonal regulation of oocyte growth and maturation in fish. Pituitary gonadotropins are of primary importance in triggering these processes in fish oocytes. In both cases, however, the actions of gonadotropins are not direct but are mediated by the follicular production of steroidal mediators, estradiol-17β (oocyte growth), and 17α,20β-dihydroxy-4-pregnene-3-one (DP) or 4-pregnen-17,20β,21-triol-3-one (20β-S) (oocyte maturation). It has been established that both estradiol- 17β and 17α,20β-DP are biosynthesized by salmonid ovarian follicles through an interaction of two cell layers—namely, the thecal and the granulosa cell layers (two-cell-type model). The granulosa cell layers are the sites of production of these two steroidal mediators, but their production depends on the provision of the precursor steroids by the thecal cell layers.
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U2 - 10.1016/S0070-2153(08)60565-7
DO - 10.1016/S0070-2153(08)60565-7
M3 - Article
C2 - 7555044
AN - SCOPUS:0028869430
SN - 0070-2153
VL - 30
SP - 103
EP - 145
JO - Current Topics in Developmental Biology
JF - Current Topics in Developmental Biology
IS - C
ER -