Relation between green tea consumption and the severity of coronary atherosclerosis among Japanese men and women

Shizuka Sasazuki, Hiroko Kodama, Kouichi Yoshimasu, Ying Liu, Masakazu Washio, Keitaro Tanaka, Shoji Tokunaga, Suminori Kono, Hidekazu Arai, Yoshitaka Doi, Tomoki Kawano, Osamu Nakagaki, Kazuyuki Takada, Samon Koyanagi, Koji Hiyamuta, Takanobu Nii, Kazuyuki Shirai, Munehito Ideishi, Kikuo Arakawa, Masahiro MohriAkira Takeshita

Research output: Contribution to journalArticlepeer-review

108 Citations (Scopus)

Abstract

PURPOSE: To examine the relation between green tea consumption and arteriographically determined coronary atherosclerosis. METHODS: Study subjects were 512 patients (302 men and 210 women) aged 30 years or older who underwent coronary arteriography for the first time at four hospitals in Fukuoka City or one hospital in an adjacent city between September 1996 and August 1997. Lifestyle characteristics including green tea consumption were ascertained before arteriography by a questionnaire supported with interview. RESULTS: 117 men (38.7%) and 50 women (23.8%) had significant stenosis of one or more coronary arteries. Green tea consumption tended to be inversely associated with coronary atherosclerosis in men, but not in women. An evident, protective association between green tea and coronary atherosclerosis was observed in a subgroup of 262 men excluding those under dietary or drug treatment for diabetes mellitus. In this subgroup, after adjustment for traditional coronary risk factors and coffee, odds ratios of significant stenosis for consumption of 2-3 cups and 4 or more cups per day were 0.5 (95% confidence interval 0.2-1.2) and 0.4 (0.2-0.9), respectively, as compared with a consumption of one cup per day or less. CONCLUSIONS: The results indicate that green tea may be protective against coronary atherosclerosis at least in men. (C) 2000 Elsevier Science Inc.

Original languageEnglish
Pages (from-to)401-408
Number of pages8
JournalAnnals of Epidemiology
Volume10
Issue number6
DOIs
Publication statusPublished - Aug 2000

All Science Journal Classification (ASJC) codes

  • Epidemiology

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