Relationship between mitochondrial haplogroup and psychophysiological responses during cold exposure in a Japanese population

Takayuki Nishimura, Midori Motoi, Yoshikazu Hoshi, Ryuichiro Kondo, Shigeki Watanuki

Research output: Contribution to journalArticle

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Abstract

The purpose of this study was to investigate the genetic factors responsible for individual differences in cold tolerance. Focusing on mitochondrial haplogroup D (D4) in Japanese subjects, differences in cold tolerance between haplogroup D subjects and other haplogroup subjects were investigated. The experiment was conducted in summer (August-September). Room temperature was decreased from 27 to 10°C in 30 min, and cold exposure was then maintained at 10°C for 60 min. During that time, measurements were made of physiological responses, including rectal temperature, skin temperature, oxygen consumption, blood pressure, and heart rate. A subjective evaluation was also made. It was found that, under cold exposure, the decrease in rectal temperature of haplogroup D subjects was significantly less than that in other groups (P < 0.001). There was no significant main group effect for oxygen consumption or mean skin temperature. In haplogroup D subjects, the thermal comfort sensation was judged to be significant discomfort at 20 and 30 min after the start of cold stimulation (P < 0.05). From the relation of oxygen consumption to rectal temperature, it is conjectured that the rectal temperature at which increased thermogenesis starts is higher in haplogroup D subjects. This study suggests that differences in mitochondrial haplogroup are one factor in individual differences in cold tolerance in Japanese.

Original languageEnglish
Pages (from-to)265-271
Number of pages7
JournalAnthropological Science
Volume119
Issue number3
DOIs
Publication statusPublished - Dec 21 2011

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tolerance
heredity
Group
experiment
evaluation
time

All Science Journal Classification (ASJC) codes

  • Anthropology

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Relationship between mitochondrial haplogroup and psychophysiological responses during cold exposure in a Japanese population. / Nishimura, Takayuki; Motoi, Midori; Hoshi, Yoshikazu; Kondo, Ryuichiro; Watanuki, Shigeki.

In: Anthropological Science, Vol. 119, No. 3, 21.12.2011, p. 265-271.

Research output: Contribution to journalArticle

Nishimura, Takayuki ; Motoi, Midori ; Hoshi, Yoshikazu ; Kondo, Ryuichiro ; Watanuki, Shigeki. / Relationship between mitochondrial haplogroup and psychophysiological responses during cold exposure in a Japanese population. In: Anthropological Science. 2011 ; Vol. 119, No. 3. pp. 265-271.
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