Lactococcus lactis IO-1 produces a peptide antibiotic, nisin Z by using glucose as well as xylose as a carbon source. To investigate the relationship between nisin Z production and aeration condition for the fermentation, fermentation was run in flask and jar fermenter with xylose and glucose. Optimal aeration condition for nisin Z production was not always that for cell growth and lactate production. The influence of aeration on nisin Z production was observed highly severe in flask-based fermentation because of uncontrolled pH condition even in the presence of CaCO3. Degradation of nisin Z produced was scarcely observed under the optimized conditions for aeration, which might give less expression of the activities of the degrading enzymes.
|Number of pages||12|
|Journal||Journal of the Faculty of Agriculture, Kyushu University|
|Publication status||Published - Mar 1 1998|
All Science Journal Classification (ASJC) codes
- Agronomy and Crop Science