Relationship between Nisin Z Fermentative Production and Aeration Condition Using Lactococcus lactis IO-1

Noppawan Chinachoti, Tomoko Zaima, Hiromi Matsusaki, Kenji Sonomoto, Ayaaki Ishizaki

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)

Abstract

Lactococcus lactis IO-1 produces a peptide antibiotic, nisin Z by using glucose as well as xylose as a carbon source. To investigate the relationship between nisin Z production and aeration condition for the fermentation, fermentation was run in flask and jar fermenter with xylose and glucose. Optimal aeration condition for nisin Z production was not always that for cell growth and lactate production. The influence of aeration on nisin Z production was observed highly severe in flask-based fermentation because of uncontrolled pH condition even in the presence of CaCO3. Degradation of nisin Z produced was scarcely observed under the optimized conditions for aeration, which might give less expression of the activities of the degrading enzymes.

Original languageEnglish
Pages (from-to)437-448
Number of pages12
JournalJournal of the Faculty of Agriculture, Kyushu University
Volume42
Issue number3-4
Publication statusPublished - Mar 1 1998

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Agronomy and Crop Science

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