Relationship between the water structure in the vicinity of carboxybetaine polymers and their biocompatibility

Susumu Tada, Kazuya Mizukami, Makoto Gemmei-Ide, Hiromi Kitano, Masaru Tanaka

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Structure of water in the vicinity of carboxybetaine(CMB), n-buthyl methacrylate(BMA) polymers and their copolymers with various compositions was investigated by using vibrational spectroscopies. Raman spectroscopy has revealed that, in contrast with ordinary polyelectrolytes, the zwitterionic polymers, PCMB and water-soluble P(BMA/CMB), did not affect the hydrogen-bonded network structure of water in their aqueous solutions. ATR-IR spectra of water sorbed into the P(BMA/CMB) films was similar to that of free water, but that in PBMA film was not. On the other hand, number of platelets adhered to the P(BMA/CMB) films was much smaller than that of PBMA film. These results suggest that the water structure is very important factor to generate biocompatibility of polymers.

Original languageEnglish
Title of host publication54th SPSJ Annual Meeting 2005 - Polymer Preprints, Japan
Pages1132
Number of pages1
Volume54
Edition1
Publication statusPublished - 2005
Externally publishedYes
Event54th SPSJ Annual Meeting 2005 - Yokohama, Japan
Duration: May 25 2005May 27 2005

Other

Other54th SPSJ Annual Meeting 2005
CountryJapan
CityYokohama
Period5/25/055/27/05

Fingerprint

Biocompatibility
Polymers
Water
Vibrational spectroscopy
Platelets
Polyelectrolytes
Raman spectroscopy
Copolymers
Hydrogen
Chemical analysis

All Science Journal Classification (ASJC) codes

  • Engineering(all)

Cite this

Tada, S., Mizukami, K., Gemmei-Ide, M., Kitano, H., & Tanaka, M. (2005). Relationship between the water structure in the vicinity of carboxybetaine polymers and their biocompatibility. In 54th SPSJ Annual Meeting 2005 - Polymer Preprints, Japan (1 ed., Vol. 54, pp. 1132)

Relationship between the water structure in the vicinity of carboxybetaine polymers and their biocompatibility. / Tada, Susumu; Mizukami, Kazuya; Gemmei-Ide, Makoto; Kitano, Hiromi; Tanaka, Masaru.

54th SPSJ Annual Meeting 2005 - Polymer Preprints, Japan. Vol. 54 1. ed. 2005. p. 1132.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Tada, S, Mizukami, K, Gemmei-Ide, M, Kitano, H & Tanaka, M 2005, Relationship between the water structure in the vicinity of carboxybetaine polymers and their biocompatibility. in 54th SPSJ Annual Meeting 2005 - Polymer Preprints, Japan. 1 edn, vol. 54, pp. 1132, 54th SPSJ Annual Meeting 2005, Yokohama, Japan, 5/25/05.
Tada S, Mizukami K, Gemmei-Ide M, Kitano H, Tanaka M. Relationship between the water structure in the vicinity of carboxybetaine polymers and their biocompatibility. In 54th SPSJ Annual Meeting 2005 - Polymer Preprints, Japan. 1 ed. Vol. 54. 2005. p. 1132
Tada, Susumu ; Mizukami, Kazuya ; Gemmei-Ide, Makoto ; Kitano, Hiromi ; Tanaka, Masaru. / Relationship between the water structure in the vicinity of carboxybetaine polymers and their biocompatibility. 54th SPSJ Annual Meeting 2005 - Polymer Preprints, Japan. Vol. 54 1. ed. 2005. pp. 1132
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