Relationship between thigmotropism and Candida biofilm formation in vitro

Hiroki Nikawa, Hiroko Nishimura, Taizo Hamada, Seicho Makihira, Lakshman P. Samaranayake

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

The biofilm formation of the oral fungal pathogen Candida on denture acrylic strips coated with saliva or serum was examined in relation to the ability to induce hyphae by thigmotropic reaction, using C. albicans (4 isolates), C. glabrata (3 isolates) and C. tropicalis (3 isolates). Both the degree of biofilm formation and the amount of hyphae exhibiting thigmotropism varied depending upon both the species and strains of Candida. Although there was no significant correlation between the amount of hyphae induced by thigmotropic reaction of fungal isolates and biofilm formation on uncoated control specimens (r = 0.577; p < 0.05), the ability of hyphae induced by thigmotropic reaction significantly correlated with the amount of both saliva- and serum-admixed biofilms (r = 0.734; p < 0.05 and r = 0.793; p < 0.01, respectively). Taken together our in vitro data suggested that the hyphal induction by thigmotropic reaction is of importance in candidal biofilm formation on saliva- or serum-coated acrylic surfaces.

Original languageEnglish
Pages (from-to)125-129
Number of pages5
JournalMycopathologia
Volume144
Issue number3
DOIs
Publication statusPublished - Dec 1 1998

Fingerprint

thigmotropism
Biofilms
Candida
biofilm
Hyphae
hyphae
saliva
Saliva
Serum
Dentures
Candida albicans
mouth
In Vitro Techniques
pathogens

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Applied Microbiology and Biotechnology
  • Agronomy and Crop Science
  • veterinary (miscalleneous)

Cite this

Nikawa, H., Nishimura, H., Hamada, T., Makihira, S., & Samaranayake, L. P. (1998). Relationship between thigmotropism and Candida biofilm formation in vitro. Mycopathologia, 144(3), 125-129. https://doi.org/10.1023/A:1007073930933

Relationship between thigmotropism and Candida biofilm formation in vitro. / Nikawa, Hiroki; Nishimura, Hiroko; Hamada, Taizo; Makihira, Seicho; Samaranayake, Lakshman P.

In: Mycopathologia, Vol. 144, No. 3, 01.12.1998, p. 125-129.

Research output: Contribution to journalArticle

Nikawa, H, Nishimura, H, Hamada, T, Makihira, S & Samaranayake, LP 1998, 'Relationship between thigmotropism and Candida biofilm formation in vitro', Mycopathologia, vol. 144, no. 3, pp. 125-129. https://doi.org/10.1023/A:1007073930933
Nikawa H, Nishimura H, Hamada T, Makihira S, Samaranayake LP. Relationship between thigmotropism and Candida biofilm formation in vitro. Mycopathologia. 1998 Dec 1;144(3):125-129. https://doi.org/10.1023/A:1007073930933
Nikawa, Hiroki ; Nishimura, Hiroko ; Hamada, Taizo ; Makihira, Seicho ; Samaranayake, Lakshman P. / Relationship between thigmotropism and Candida biofilm formation in vitro. In: Mycopathologia. 1998 ; Vol. 144, No. 3. pp. 125-129.
@article{28c6752ae88c4cf5aadabb99d0045067,
title = "Relationship between thigmotropism and Candida biofilm formation in vitro",
abstract = "The biofilm formation of the oral fungal pathogen Candida on denture acrylic strips coated with saliva or serum was examined in relation to the ability to induce hyphae by thigmotropic reaction, using C. albicans (4 isolates), C. glabrata (3 isolates) and C. tropicalis (3 isolates). Both the degree of biofilm formation and the amount of hyphae exhibiting thigmotropism varied depending upon both the species and strains of Candida. Although there was no significant correlation between the amount of hyphae induced by thigmotropic reaction of fungal isolates and biofilm formation on uncoated control specimens (r = 0.577; p < 0.05), the ability of hyphae induced by thigmotropic reaction significantly correlated with the amount of both saliva- and serum-admixed biofilms (r = 0.734; p < 0.05 and r = 0.793; p < 0.01, respectively). Taken together our in vitro data suggested that the hyphal induction by thigmotropic reaction is of importance in candidal biofilm formation on saliva- or serum-coated acrylic surfaces.",
author = "Hiroki Nikawa and Hiroko Nishimura and Taizo Hamada and Seicho Makihira and Samaranayake, {Lakshman P.}",
year = "1998",
month = "12",
day = "1",
doi = "10.1023/A:1007073930933",
language = "English",
volume = "144",
pages = "125--129",
journal = "Mycopathologia",
issn = "0301-486X",
publisher = "Springer Netherlands",
number = "3",

}

TY - JOUR

T1 - Relationship between thigmotropism and Candida biofilm formation in vitro

AU - Nikawa, Hiroki

AU - Nishimura, Hiroko

AU - Hamada, Taizo

AU - Makihira, Seicho

AU - Samaranayake, Lakshman P.

PY - 1998/12/1

Y1 - 1998/12/1

N2 - The biofilm formation of the oral fungal pathogen Candida on denture acrylic strips coated with saliva or serum was examined in relation to the ability to induce hyphae by thigmotropic reaction, using C. albicans (4 isolates), C. glabrata (3 isolates) and C. tropicalis (3 isolates). Both the degree of biofilm formation and the amount of hyphae exhibiting thigmotropism varied depending upon both the species and strains of Candida. Although there was no significant correlation between the amount of hyphae induced by thigmotropic reaction of fungal isolates and biofilm formation on uncoated control specimens (r = 0.577; p < 0.05), the ability of hyphae induced by thigmotropic reaction significantly correlated with the amount of both saliva- and serum-admixed biofilms (r = 0.734; p < 0.05 and r = 0.793; p < 0.01, respectively). Taken together our in vitro data suggested that the hyphal induction by thigmotropic reaction is of importance in candidal biofilm formation on saliva- or serum-coated acrylic surfaces.

AB - The biofilm formation of the oral fungal pathogen Candida on denture acrylic strips coated with saliva or serum was examined in relation to the ability to induce hyphae by thigmotropic reaction, using C. albicans (4 isolates), C. glabrata (3 isolates) and C. tropicalis (3 isolates). Both the degree of biofilm formation and the amount of hyphae exhibiting thigmotropism varied depending upon both the species and strains of Candida. Although there was no significant correlation between the amount of hyphae induced by thigmotropic reaction of fungal isolates and biofilm formation on uncoated control specimens (r = 0.577; p < 0.05), the ability of hyphae induced by thigmotropic reaction significantly correlated with the amount of both saliva- and serum-admixed biofilms (r = 0.734; p < 0.05 and r = 0.793; p < 0.01, respectively). Taken together our in vitro data suggested that the hyphal induction by thigmotropic reaction is of importance in candidal biofilm formation on saliva- or serum-coated acrylic surfaces.

UR - http://www.scopus.com/inward/record.url?scp=0032322468&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032322468&partnerID=8YFLogxK

U2 - 10.1023/A:1007073930933

DO - 10.1023/A:1007073930933

M3 - Article

C2 - 10531677

AN - SCOPUS:0032322468

VL - 144

SP - 125

EP - 129

JO - Mycopathologia

JF - Mycopathologia

SN - 0301-486X

IS - 3

ER -