Relationships among differentiated T-cell subpopulations. III. Radioresistance of delayed hypersensitivity to heterologous erythrocytes

K. Nomoto, K. Taniguchi, Chiharu Kubo, K. Takeya

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Effects of whole body irradiation with 600 rad on delayed hypersensitivity, direct cytotoxicity and antibody production were examined in mice immunized with chicken erythrocytes (CRBC) or sheep erythrocytes (SRBC) in saline. Delayed footpad reactions to CRBC were not affected by the exposure to irradiation 3 h before or after antigenic stimulation. On the other hand, direct cytotoxic activities in spleen cells and antibody titres to CRBC were reduced by such exposures. Additionally, delayed footpad reactions to SRBC were not affected by the exposure to irradiation. Generation of effector cells responsible for delayed footpad reactions proved to be resistant to irradiation.

Original languageEnglish
Pages (from-to)517-521
Number of pages5
JournalImmunology
Volume34
Issue number3
Publication statusPublished - 1978

Fingerprint

Delayed Hypersensitivity
Erythrocytes
T-Lymphocytes
Whole-Body Irradiation
Antibody Formation
Chickens
Sheep
Spleen
Antibodies

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology

Cite this

Relationships among differentiated T-cell subpopulations. III. Radioresistance of delayed hypersensitivity to heterologous erythrocytes. / Nomoto, K.; Taniguchi, K.; Kubo, Chiharu; Takeya, K.

In: Immunology, Vol. 34, No. 3, 1978, p. 517-521.

Research output: Contribution to journalArticle

@article{4aaa446cc83c4b3bba4c4a014e6e7c99,
title = "Relationships among differentiated T-cell subpopulations. III. Radioresistance of delayed hypersensitivity to heterologous erythrocytes",
abstract = "Effects of whole body irradiation with 600 rad on delayed hypersensitivity, direct cytotoxicity and antibody production were examined in mice immunized with chicken erythrocytes (CRBC) or sheep erythrocytes (SRBC) in saline. Delayed footpad reactions to CRBC were not affected by the exposure to irradiation 3 h before or after antigenic stimulation. On the other hand, direct cytotoxic activities in spleen cells and antibody titres to CRBC were reduced by such exposures. Additionally, delayed footpad reactions to SRBC were not affected by the exposure to irradiation. Generation of effector cells responsible for delayed footpad reactions proved to be resistant to irradiation.",
author = "K. Nomoto and K. Taniguchi and Chiharu Kubo and K. Takeya",
year = "1978",
language = "English",
volume = "34",
pages = "517--521",
journal = "Immunology",
issn = "0019-2805",
publisher = "Wiley-Blackwell",
number = "3",

}

TY - JOUR

T1 - Relationships among differentiated T-cell subpopulations. III. Radioresistance of delayed hypersensitivity to heterologous erythrocytes

AU - Nomoto, K.

AU - Taniguchi, K.

AU - Kubo, Chiharu

AU - Takeya, K.

PY - 1978

Y1 - 1978

N2 - Effects of whole body irradiation with 600 rad on delayed hypersensitivity, direct cytotoxicity and antibody production were examined in mice immunized with chicken erythrocytes (CRBC) or sheep erythrocytes (SRBC) in saline. Delayed footpad reactions to CRBC were not affected by the exposure to irradiation 3 h before or after antigenic stimulation. On the other hand, direct cytotoxic activities in spleen cells and antibody titres to CRBC were reduced by such exposures. Additionally, delayed footpad reactions to SRBC were not affected by the exposure to irradiation. Generation of effector cells responsible for delayed footpad reactions proved to be resistant to irradiation.

AB - Effects of whole body irradiation with 600 rad on delayed hypersensitivity, direct cytotoxicity and antibody production were examined in mice immunized with chicken erythrocytes (CRBC) or sheep erythrocytes (SRBC) in saline. Delayed footpad reactions to CRBC were not affected by the exposure to irradiation 3 h before or after antigenic stimulation. On the other hand, direct cytotoxic activities in spleen cells and antibody titres to CRBC were reduced by such exposures. Additionally, delayed footpad reactions to SRBC were not affected by the exposure to irradiation. Generation of effector cells responsible for delayed footpad reactions proved to be resistant to irradiation.

UR - http://www.scopus.com/inward/record.url?scp=0018178725&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018178725&partnerID=8YFLogxK

M3 - Article

C2 - 305892

AN - SCOPUS:0018178725

VL - 34

SP - 517

EP - 521

JO - Immunology

JF - Immunology

SN - 0019-2805

IS - 3

ER -