Remifentanil não aumenta a diurese durante cirurgia oral, contrariamente ao seu efeito durante outras cirurgias – estudo de coorte

Translated title of the contribution: Remifentanil does not increase urine output during oral surgery, contrary to its effect during other surgeries – a cohort study

Kentaro Ouchi, Kazuna Sugiyama

Research output: Contribution to journalArticle

Abstract

Background An increase in urine output by remifentanil injection during laparoscopic procedures and surgeries such as cardiac and gynecological procedures, due to suppression of the stress response to surgery, has been reported. The aim of our prospective, observational, cohort study was to assess the effect of remifentanil analgesia on urine output during dental and minor oral surgery by comparing intraoperative urine output under defined infusion volumes with and without the use of remifentanil. Methods Dental patients aged 16 years or older, American Society of Anesthesiologists physical status 1, with no renal diseases or abnormal blood values of serum creatinine and BUN, not on treatment with diuretic drugs, and undergoing minor oro‐maxillofacial surgery or dental treatment under inhalation general anesthesia were included in this study. Urethral catheterization was performed after anesthesia induction, and urine output was measured every 30 minutes. We measured urine volume (mL) and rate of urine output (mL.kg −1 .h −1 ) intraoperatively, and compared these parameters between patients who did and did not receive remifentanil during the intraoperative period. Results Eighty‐seven patients were categorized into the remifentanil group (n = 43) or remifentanil non‐use group (n = 44). Both volume of urine (mL) and rate of urine output (mL.kg −1 .h −1 ) were not significantly different between the two groups (remifentanil group, 372.3 ± 273.5 mL, 1.8 ± 1.1 mL.kg −1 .h −1 ; remifentanil non‐use group, 343.3 ± 283.3 mL, 1.9 ± 1.2 mL.kg −1 .h −1 ; p = 0.63; 0.57). Conclusion Our results show that use of remifentanil during dental and minor oral surgeries does not increase urine output.

Original languagePortuguese
Pages (from-to)342-346
Number of pages5
JournalBrazilian Journal of Anesthesiology
Volume67
Issue number4
DOIs
Publication statusPublished - Jul 1 2017

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Oral Surgery
Cohort Studies
Urine
Minor Surgical Procedures
Tooth
Intraoperative Period
Inhalation Anesthesia
Urinary Catheterization
remifentanil
Blood Urea Nitrogen
Diuretics
Laparoscopy
Analgesia
General Anesthesia
Observational Studies
Creatinine
Anesthesia
Kidney
Injections
Therapeutics

All Science Journal Classification (ASJC) codes

  • Anesthesiology and Pain Medicine

Cite this

Remifentanil não aumenta a diurese durante cirurgia oral, contrariamente ao seu efeito durante outras cirurgias – estudo de coorte. / Ouchi, Kentaro; Sugiyama, Kazuna.

In: Brazilian Journal of Anesthesiology, Vol. 67, No. 4, 01.07.2017, p. 342-346.

Research output: Contribution to journalArticle

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abstract = "Background An increase in urine output by remifentanil injection during laparoscopic procedures and surgeries such as cardiac and gynecological procedures, due to suppression of the stress response to surgery, has been reported. The aim of our prospective, observational, cohort study was to assess the effect of remifentanil analgesia on urine output during dental and minor oral surgery by comparing intraoperative urine output under defined infusion volumes with and without the use of remifentanil. Methods Dental patients aged 16 years or older, American Society of Anesthesiologists physical status 1, with no renal diseases or abnormal blood values of serum creatinine and BUN, not on treatment with diuretic drugs, and undergoing minor oro‐maxillofacial surgery or dental treatment under inhalation general anesthesia were included in this study. Urethral catheterization was performed after anesthesia induction, and urine output was measured every 30 minutes. We measured urine volume (mL) and rate of urine output (mL.kg −1 .h −1 ) intraoperatively, and compared these parameters between patients who did and did not receive remifentanil during the intraoperative period. Results Eighty‐seven patients were categorized into the remifentanil group (n = 43) or remifentanil non‐use group (n = 44). Both volume of urine (mL) and rate of urine output (mL.kg −1 .h −1 ) were not significantly different between the two groups (remifentanil group, 372.3 ± 273.5 mL, 1.8 ± 1.1 mL.kg −1 .h −1 ; remifentanil non‐use group, 343.3 ± 283.3 mL, 1.9 ± 1.2 mL.kg −1 .h −1 ; p = 0.63; 0.57). Conclusion Our results show that use of remifentanil during dental and minor oral surgeries does not increase urine output.",
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N2 - Background An increase in urine output by remifentanil injection during laparoscopic procedures and surgeries such as cardiac and gynecological procedures, due to suppression of the stress response to surgery, has been reported. The aim of our prospective, observational, cohort study was to assess the effect of remifentanil analgesia on urine output during dental and minor oral surgery by comparing intraoperative urine output under defined infusion volumes with and without the use of remifentanil. Methods Dental patients aged 16 years or older, American Society of Anesthesiologists physical status 1, with no renal diseases or abnormal blood values of serum creatinine and BUN, not on treatment with diuretic drugs, and undergoing minor oro‐maxillofacial surgery or dental treatment under inhalation general anesthesia were included in this study. Urethral catheterization was performed after anesthesia induction, and urine output was measured every 30 minutes. We measured urine volume (mL) and rate of urine output (mL.kg −1 .h −1 ) intraoperatively, and compared these parameters between patients who did and did not receive remifentanil during the intraoperative period. Results Eighty‐seven patients were categorized into the remifentanil group (n = 43) or remifentanil non‐use group (n = 44). Both volume of urine (mL) and rate of urine output (mL.kg −1 .h −1 ) were not significantly different between the two groups (remifentanil group, 372.3 ± 273.5 mL, 1.8 ± 1.1 mL.kg −1 .h −1 ; remifentanil non‐use group, 343.3 ± 283.3 mL, 1.9 ± 1.2 mL.kg −1 .h −1 ; p = 0.63; 0.57). Conclusion Our results show that use of remifentanil during dental and minor oral surgeries does not increase urine output.

AB - Background An increase in urine output by remifentanil injection during laparoscopic procedures and surgeries such as cardiac and gynecological procedures, due to suppression of the stress response to surgery, has been reported. The aim of our prospective, observational, cohort study was to assess the effect of remifentanil analgesia on urine output during dental and minor oral surgery by comparing intraoperative urine output under defined infusion volumes with and without the use of remifentanil. Methods Dental patients aged 16 years or older, American Society of Anesthesiologists physical status 1, with no renal diseases or abnormal blood values of serum creatinine and BUN, not on treatment with diuretic drugs, and undergoing minor oro‐maxillofacial surgery or dental treatment under inhalation general anesthesia were included in this study. Urethral catheterization was performed after anesthesia induction, and urine output was measured every 30 minutes. We measured urine volume (mL) and rate of urine output (mL.kg −1 .h −1 ) intraoperatively, and compared these parameters between patients who did and did not receive remifentanil during the intraoperative period. Results Eighty‐seven patients were categorized into the remifentanil group (n = 43) or remifentanil non‐use group (n = 44). Both volume of urine (mL) and rate of urine output (mL.kg −1 .h −1 ) were not significantly different between the two groups (remifentanil group, 372.3 ± 273.5 mL, 1.8 ± 1.1 mL.kg −1 .h −1 ; remifentanil non‐use group, 343.3 ± 283.3 mL, 1.9 ± 1.2 mL.kg −1 .h −1 ; p = 0.63; 0.57). Conclusion Our results show that use of remifentanil during dental and minor oral surgeries does not increase urine output.

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