Abstract
A 68-year-old man underwent a partial resection of the liver and lymph node dissection for a tumor, 3.0 cm in diameter, in S4 of the liver under the diagnosis of cholangiocellular carcinoma (CCC). The histological diagnosis was cholangiolocellular carcinoma (CoCC) and lymphatic permeation and venous invasion were recognized. Seven months after surgery, CT demonstrated two recurrent nodules in S7 and S8 of the liver, then a partial resection of the liver was performed. The gross and pathological findings were the same as the previously resected tumor. Four months after the second operation, CT demonstrated dilated intrahepatic bile ducts and lymph node swelling of the hepatic hilum. The patient died of disease thirteen months after the first operation. On the basis of the clinical and pathological features of this case, we consider that CoCC clinically resembles CCC and prognosis may be unfavorable, although it has characteristic pathological findings. It is still controversial whether CoCC should be accepted as a separate entity. The significance of repeat hepatectomy for recurrence and adjuvant chemotherapy should be clarified to improve the prognosis of CoCC.
| Original language | English |
|---|---|
| Pages (from-to) | 564-568 |
| Number of pages | 5 |
| Journal | Fukuoka igaku zasshi = Hukuoka acta medica |
| Volume | 104 |
| Issue number | 12 |
| Publication status | Published - Jan 1 2013 |
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All Science Journal Classification (ASJC) codes
- Medicine(all)
Cite this
Repeat hepatectomy for intrahepatic recurrence of cholangiolocellular carcinoma. / Maeda, Takashi; Hashimoto, Koji; Ishida, Teruyoshi; Yamashita, Yo Ichi; Saeki, Hiroshi; Kawanaka, Hirofumi; Uchiyama, Hideaki; Ikeda, Tetsuo; Tsujitani, Shunichi; Maehara, Yoshihiko.
In: Fukuoka igaku zasshi = Hukuoka acta medica, Vol. 104, No. 12, 01.01.2013, p. 564-568.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Repeat hepatectomy for intrahepatic recurrence of cholangiolocellular carcinoma.
AU - Maeda, Takashi
AU - Hashimoto, Koji
AU - Ishida, Teruyoshi
AU - Yamashita, Yo Ichi
AU - Saeki, Hiroshi
AU - Kawanaka, Hirofumi
AU - Uchiyama, Hideaki
AU - Ikeda, Tetsuo
AU - Tsujitani, Shunichi
AU - Maehara, Yoshihiko
PY - 2013/1/1
Y1 - 2013/1/1
N2 - A 68-year-old man underwent a partial resection of the liver and lymph node dissection for a tumor, 3.0 cm in diameter, in S4 of the liver under the diagnosis of cholangiocellular carcinoma (CCC). The histological diagnosis was cholangiolocellular carcinoma (CoCC) and lymphatic permeation and venous invasion were recognized. Seven months after surgery, CT demonstrated two recurrent nodules in S7 and S8 of the liver, then a partial resection of the liver was performed. The gross and pathological findings were the same as the previously resected tumor. Four months after the second operation, CT demonstrated dilated intrahepatic bile ducts and lymph node swelling of the hepatic hilum. The patient died of disease thirteen months after the first operation. On the basis of the clinical and pathological features of this case, we consider that CoCC clinically resembles CCC and prognosis may be unfavorable, although it has characteristic pathological findings. It is still controversial whether CoCC should be accepted as a separate entity. The significance of repeat hepatectomy for recurrence and adjuvant chemotherapy should be clarified to improve the prognosis of CoCC.
AB - A 68-year-old man underwent a partial resection of the liver and lymph node dissection for a tumor, 3.0 cm in diameter, in S4 of the liver under the diagnosis of cholangiocellular carcinoma (CCC). The histological diagnosis was cholangiolocellular carcinoma (CoCC) and lymphatic permeation and venous invasion were recognized. Seven months after surgery, CT demonstrated two recurrent nodules in S7 and S8 of the liver, then a partial resection of the liver was performed. The gross and pathological findings were the same as the previously resected tumor. Four months after the second operation, CT demonstrated dilated intrahepatic bile ducts and lymph node swelling of the hepatic hilum. The patient died of disease thirteen months after the first operation. On the basis of the clinical and pathological features of this case, we consider that CoCC clinically resembles CCC and prognosis may be unfavorable, although it has characteristic pathological findings. It is still controversial whether CoCC should be accepted as a separate entity. The significance of repeat hepatectomy for recurrence and adjuvant chemotherapy should be clarified to improve the prognosis of CoCC.
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UR - http://www.scopus.com/inward/citedby.url?scp=84900000399&partnerID=8YFLogxK
M3 - Article
C2 - 24693685
AN - SCOPUS:84900000399
VL - 104
SP - 564
EP - 568
JO - Fukuoka Acta Medica
JF - Fukuoka Acta Medica
SN - 0016-254X
IS - 12
ER -