Resected peripheral small cell carcinoma of the lung: Computed tomographic-histologic correlation

Hidetake Yabuuchi, Sadayuki Murayama, Shuji Sakai, Norihisa Hashiguchi, Junji Murakami, Toru Muranaka, Hiroyasu Soeda, Kenji Sugio, Akira Nagashima, Kouji Masuda

Research output: Contribution to journalArticle

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Abstract

In order to clarify the characteristic computed tomographic findings of peripheral small cell lung cancer, the authors investigated 12 patients with surgically resected and histologically proven peripheral small cell lung cancer. Conventional computed tomography was performed on all, and additional high-resolution computed tomographic images were obtained for nine patients. Marginal, internal, and surrounding features of the tumors were analyzed, and these findings were correlated with histologic findings. All 12 tumors appeared as homogenous masses, and eight had well-defined margins. Lobulation was found in seven, marginal ground-glass opacity in three, fine spiculation in two, and both ground-glass opacity and spiculation in one. Cut specimens showed whitish medullary masses without large areas of necrosis, and microscopic specimens showed small areas of necrosis in 11 patients. Marginal ground-glass opacities corresponded to focal edema and hemorrhage in two patients and to intraalveolar invasion in one. Fine spiculation corresponded to vascular/lymphatic invasion in one patient and to irregular intraalveolar spread in another. The authors concluded that a homogenous mass without necrosis is the most characteristic feature of peripheral small cell carcinoma on computed tomography.

Original languageEnglish
Pages (from-to)105-108
Number of pages4
JournalJournal of Thoracic Imaging
Volume14
Issue number2
DOIs
Publication statusPublished - Jan 1 1999

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Small Cell Lung Carcinoma
Glass
Necrosis
Tomography
Small Cell Carcinoma
Blood Vessels
Edema
Neoplasms
Hemorrhage

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Pulmonary and Respiratory Medicine

Cite this

Resected peripheral small cell carcinoma of the lung : Computed tomographic-histologic correlation. / Yabuuchi, Hidetake; Murayama, Sadayuki; Sakai, Shuji; Hashiguchi, Norihisa; Murakami, Junji; Muranaka, Toru; Soeda, Hiroyasu; Sugio, Kenji; Nagashima, Akira; Masuda, Kouji.

In: Journal of Thoracic Imaging, Vol. 14, No. 2, 01.01.1999, p. 105-108.

Research output: Contribution to journalArticle

Yabuuchi, H, Murayama, S, Sakai, S, Hashiguchi, N, Murakami, J, Muranaka, T, Soeda, H, Sugio, K, Nagashima, A & Masuda, K 1999, 'Resected peripheral small cell carcinoma of the lung: Computed tomographic-histologic correlation', Journal of Thoracic Imaging, vol. 14, no. 2, pp. 105-108. https://doi.org/10.1097/00005382-199904000-00007
Yabuuchi, Hidetake ; Murayama, Sadayuki ; Sakai, Shuji ; Hashiguchi, Norihisa ; Murakami, Junji ; Muranaka, Toru ; Soeda, Hiroyasu ; Sugio, Kenji ; Nagashima, Akira ; Masuda, Kouji. / Resected peripheral small cell carcinoma of the lung : Computed tomographic-histologic correlation. In: Journal of Thoracic Imaging. 1999 ; Vol. 14, No. 2. pp. 105-108.
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