Restoration of Ca2+-activated tension of CDTA-treated single skeletal muscle fibers by troponin C

Sachio Morimoto, Takashi Fujiwara, Iwao Ohtsuki

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9 Citations (Scopus)


Single fibers from glycerinated rabbit psoas muscle were treated with a solution containing CDTA, a strong chelator of metal ions. The CDTA-treated fibers lost all of the troponin C and showed no Ca2+ tension development. The addition of troponin C restored the Ca2+ -activated tension of CDTA-treated fibers. The tension-pCa relationship in the case of the CDTA-treated fibers reconstituted with troponin C was almost the same as that in the case of the same fibers before the CDTA treatment. These results are consistent with those of the previous study on the Ca2+ -activated ATPase of CDTA-treated rabbit skeletal myofibrils (Morimoto, S.& Ohtsuki, I. (1987) J. Biochem. 101, 291-301).

Original languageEnglish
Pages (from-to)873-874
Number of pages2
JournalJournal of biochemistry
Issue number6
Publication statusPublished - Dec 1988

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology


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