Results of a safety test for proton beam therapy equipment at the Proton Medical Research Center (PMRC), University of Tsukuba

Koichi Tokuuye, Yasuyuki Akine, Yoshiyuki Shioyama, Kenji Kagei, Shinji Sugahara, Hiroshi Igaki, Masaharu Hata, Kiyoshi Ohara, Takayuki Hashimoto

Research output: Contribution to journalArticle

Abstract

A new hospital-based proton radiotherapy facility having two treatment rooms with a rotating gantry each and an experiment room with two horizontal beam ports was built at the Proton Medical Research Center (PMRC), University of Tsukuba. We started proton beam therapy as a clinical study to test the safety of the treatment equipment in September 2001. Six patients, a patient with liver metastases from ovarian carcinoma, two patients with lung carcinoma, a patient with cholangiocarcinoma, a patient with local recurrence of rectal carcinoma and a patient with bone metastasis from breast carcinoma, were enrolled in the study. They were considered unsuitable for other modalities of treatment, and were treated by proton beam therapy alone according to the methods used in the old facility at the University of Tsukuba. They were evaluated with regard to unexpected occurrences due to treatment equipment failures and treatment related toxicities. We observed no occurrence of hazardous events to the patients and no toxicities greater than grade II skin toxicities in the six patients. The results showed that the treatment system was safe and reliable for proton beam therapy.

Original languageEnglish
Pages (from-to)277-283
Number of pages7
JournalJournal of JASTRO
Volume15
Issue number4
Publication statusPublished - Dec 2003

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Oncology

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