Results of laparoscopic splenectomy for immune thrombocytopenic purpura

Kazuo Tanoue, Makoto Hashizume, Makoto Morita, Shinichiro Migoh, Kohgi Tsugawa, Seiji Yagi, Masayuki Ohta, Keizo Sugimachi

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

BACKGROUND: Laparoscopic splenectomy has been demonstrated to be technically feasible and safe for the treatment of immune thrombocytopenic purpura (ITP), hereditary spherocytosis, and Hodgkin's disease. PATIENTS AND METHODS: The study comprised 76 consecutive patients with chronic ITP who were admitted to our hospital from 1968 to 1997 and underwent splenectomy; 35 patients underwent a laparoscopic splenectomy, and 41 had open surgery. RESULTS: Laparoscopic splenectomy involved minimal incision, and a significantly lower frequency of analgesia was required for postoperative abdominal pain (1.4 versus 3.3); postoperative hospital stay was shorter (9.6 versus 20.1 days, P <0.05). Operative time was significantly longer for the laparoscopic surgery (204.5 versus 99.8 minutes, P <0.01), but blood loss was less (154.4 versus 511.7 g, P <0.01). During the present study (range 3.8 to 80 months), accumulative nonrecurrence rate was 67.9% in 5 years after surgery, which is similar to that of the previous open splenectomy. CONCLUSIONS: Laparoscopic splenectomy can become an alternative therapeutic modality in the treatment of ITP.

Original languageEnglish
Pages (from-to)222-226
Number of pages5
JournalAmerican Journal of Surgery
Volume177
Issue number3
DOIs
Publication statusPublished - Mar 1999

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Idiopathic Thrombocytopenic Purpura
Splenectomy
Hereditary Spherocytosis
Inborn Genetic Diseases
Operative Time
Postoperative Pain
Hodgkin Disease
Laparoscopy
Analgesia
Abdominal Pain
Length of Stay
Therapeutics

All Science Journal Classification (ASJC) codes

  • Surgery

Cite this

Tanoue, K., Hashizume, M., Morita, M., Migoh, S., Tsugawa, K., Yagi, S., ... Sugimachi, K. (1999). Results of laparoscopic splenectomy for immune thrombocytopenic purpura. American Journal of Surgery, 177(3), 222-226. https://doi.org/10.1016/S0002-9610(99)00014-8

Results of laparoscopic splenectomy for immune thrombocytopenic purpura. / Tanoue, Kazuo; Hashizume, Makoto; Morita, Makoto; Migoh, Shinichiro; Tsugawa, Kohgi; Yagi, Seiji; Ohta, Masayuki; Sugimachi, Keizo.

In: American Journal of Surgery, Vol. 177, No. 3, 03.1999, p. 222-226.

Research output: Contribution to journalArticle

Tanoue, K, Hashizume, M, Morita, M, Migoh, S, Tsugawa, K, Yagi, S, Ohta, M & Sugimachi, K 1999, 'Results of laparoscopic splenectomy for immune thrombocytopenic purpura', American Journal of Surgery, vol. 177, no. 3, pp. 222-226. https://doi.org/10.1016/S0002-9610(99)00014-8
Tanoue K, Hashizume M, Morita M, Migoh S, Tsugawa K, Yagi S et al. Results of laparoscopic splenectomy for immune thrombocytopenic purpura. American Journal of Surgery. 1999 Mar;177(3):222-226. https://doi.org/10.1016/S0002-9610(99)00014-8
Tanoue, Kazuo ; Hashizume, Makoto ; Morita, Makoto ; Migoh, Shinichiro ; Tsugawa, Kohgi ; Yagi, Seiji ; Ohta, Masayuki ; Sugimachi, Keizo. / Results of laparoscopic splenectomy for immune thrombocytopenic purpura. In: American Journal of Surgery. 1999 ; Vol. 177, No. 3. pp. 222-226.
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