Abstract
BACKGROUND: Laparoscopic splenectomy has been demonstrated to be technically feasible and safe for the treatment of immune thrombocytopenic purpura (ITP), hereditary spherocytosis, and Hodgkin's disease. PATIENTS AND METHODS: The study comprised 76 consecutive patients with chronic ITP who were admitted to our hospital from 1968 to 1997 and underwent splenectomy; 35 patients underwent a laparoscopic splenectomy, and 41 had open surgery. RESULTS: Laparoscopic splenectomy involved minimal incision, and a significantly lower frequency of analgesia was required for postoperative abdominal pain (1.4 versus 3.3); postoperative hospital stay was shorter (9.6 versus 20.1 days, P <0.05). Operative time was significantly longer for the laparoscopic surgery (204.5 versus 99.8 minutes, P <0.01), but blood loss was less (154.4 versus 511.7 g, P <0.01). During the present study (range 3.8 to 80 months), accumulative nonrecurrence rate was 67.9% in 5 years after surgery, which is similar to that of the previous open splenectomy. CONCLUSIONS: Laparoscopic splenectomy can become an alternative therapeutic modality in the treatment of ITP.
| Original language | English |
|---|---|
| Pages (from-to) | 222-226 |
| Number of pages | 5 |
| Journal | American Journal of Surgery |
| Volume | 177 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Mar 1999 |
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All Science Journal Classification (ASJC) codes
- Surgery
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Results of laparoscopic splenectomy for immune thrombocytopenic purpura. / Tanoue, Kazuo; Hashizume, Makoto; Morita, Makoto; Migoh, Shinichiro; Tsugawa, Kohgi; Yagi, Seiji; Ohta, Masayuki; Sugimachi, Keizo.
In: American Journal of Surgery, Vol. 177, No. 3, 03.1999, p. 222-226.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Results of laparoscopic splenectomy for immune thrombocytopenic purpura
AU - Tanoue, Kazuo
AU - Hashizume, Makoto
AU - Morita, Makoto
AU - Migoh, Shinichiro
AU - Tsugawa, Kohgi
AU - Yagi, Seiji
AU - Ohta, Masayuki
AU - Sugimachi, Keizo
PY - 1999/3
Y1 - 1999/3
N2 - BACKGROUND: Laparoscopic splenectomy has been demonstrated to be technically feasible and safe for the treatment of immune thrombocytopenic purpura (ITP), hereditary spherocytosis, and Hodgkin's disease. PATIENTS AND METHODS: The study comprised 76 consecutive patients with chronic ITP who were admitted to our hospital from 1968 to 1997 and underwent splenectomy; 35 patients underwent a laparoscopic splenectomy, and 41 had open surgery. RESULTS: Laparoscopic splenectomy involved minimal incision, and a significantly lower frequency of analgesia was required for postoperative abdominal pain (1.4 versus 3.3); postoperative hospital stay was shorter (9.6 versus 20.1 days, P <0.05). Operative time was significantly longer for the laparoscopic surgery (204.5 versus 99.8 minutes, P <0.01), but blood loss was less (154.4 versus 511.7 g, P <0.01). During the present study (range 3.8 to 80 months), accumulative nonrecurrence rate was 67.9% in 5 years after surgery, which is similar to that of the previous open splenectomy. CONCLUSIONS: Laparoscopic splenectomy can become an alternative therapeutic modality in the treatment of ITP.
AB - BACKGROUND: Laparoscopic splenectomy has been demonstrated to be technically feasible and safe for the treatment of immune thrombocytopenic purpura (ITP), hereditary spherocytosis, and Hodgkin's disease. PATIENTS AND METHODS: The study comprised 76 consecutive patients with chronic ITP who were admitted to our hospital from 1968 to 1997 and underwent splenectomy; 35 patients underwent a laparoscopic splenectomy, and 41 had open surgery. RESULTS: Laparoscopic splenectomy involved minimal incision, and a significantly lower frequency of analgesia was required for postoperative abdominal pain (1.4 versus 3.3); postoperative hospital stay was shorter (9.6 versus 20.1 days, P <0.05). Operative time was significantly longer for the laparoscopic surgery (204.5 versus 99.8 minutes, P <0.01), but blood loss was less (154.4 versus 511.7 g, P <0.01). During the present study (range 3.8 to 80 months), accumulative nonrecurrence rate was 67.9% in 5 years after surgery, which is similar to that of the previous open splenectomy. CONCLUSIONS: Laparoscopic splenectomy can become an alternative therapeutic modality in the treatment of ITP.
UR - http://www.scopus.com/inward/record.url?scp=0032948433&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032948433&partnerID=8YFLogxK
U2 - 10.1016/S0002-9610(99)00014-8
DO - 10.1016/S0002-9610(99)00014-8
M3 - Article
C2 - 10219858
AN - SCOPUS:0032948433
VL - 177
SP - 222
EP - 226
JO - American Journal of Surgery
JF - American Journal of Surgery
SN - 0002-9610
IS - 3
ER -