Abstract
We report here the ribosomal synthesis of methyllanthionine-containing cyclic peptides involving a site-specific incorporation of vinylglycine under the reprogrammed genetic code, followed by the isomerization of the vinylglycine to dehydrobutyrine, and the subsequent intramolecular Michael addition of a cysteine residue placed at a downstream position of the vinylglycine.
| Original language | English |
|---|---|
| Pages (from-to) | 3419-3421 |
| Number of pages | 3 |
| Journal | Chemical Communications |
| Issue number | 23 |
| DOIs | |
| Publication status | Published - Aug 7 2009 |
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All Science Journal Classification (ASJC) codes
- Catalysis
- Electronic, Optical and Magnetic Materials
- Ceramics and Composites
- Chemistry(all)
- Surfaces, Coatings and Films
- Metals and Alloys
- Materials Chemistry
Cite this
Ribosomal synthesis of dehydrobutyrine- and methyllanthionine-containing peptides. / Goto, Yuki; Iwasaki, Kazuhiro; Torikai, Kohei; Murakami, Hiroshi; Suga, Hiroaki.
In: Chemical Communications, No. 23, 07.08.2009, p. 3419-3421.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Ribosomal synthesis of dehydrobutyrine- and methyllanthionine-containing peptides
AU - Goto, Yuki
AU - Iwasaki, Kazuhiro
AU - Torikai, Kohei
AU - Murakami, Hiroshi
AU - Suga, Hiroaki
PY - 2009/8/7
Y1 - 2009/8/7
N2 - We report here the ribosomal synthesis of methyllanthionine-containing cyclic peptides involving a site-specific incorporation of vinylglycine under the reprogrammed genetic code, followed by the isomerization of the vinylglycine to dehydrobutyrine, and the subsequent intramolecular Michael addition of a cysteine residue placed at a downstream position of the vinylglycine.
AB - We report here the ribosomal synthesis of methyllanthionine-containing cyclic peptides involving a site-specific incorporation of vinylglycine under the reprogrammed genetic code, followed by the isomerization of the vinylglycine to dehydrobutyrine, and the subsequent intramolecular Michael addition of a cysteine residue placed at a downstream position of the vinylglycine.
UR - http://www.scopus.com/inward/record.url?scp=68049148252&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=68049148252&partnerID=8YFLogxK
U2 - 10.1039/b904314d
DO - 10.1039/b904314d
M3 - Article
C2 - 19503890
AN - SCOPUS:68049148252
SP - 3419
EP - 3421
JO - Chemical Communications
JF - Chemical Communications
SN - 1359-7345
IS - 23
ER -