Risk classification of clinically localized prostate cancer: Data from clinicopathological research for localized prostate cancer (CRPC)

The 3 level D'Amico risk classification is widely used to predict the risk of treatment failure after radical prostatectomy for localized prostate cancer. Since it has been reported that there was a considerable overlap of outcomes between the intermediate- and high-risk groups, simply estimating disease aggressiveness by stratifying patients into low-, intermediate- and high-risk groups may not provide sufficient information for predicting outcomes among individuals. The widely used Partin nomogram (Partin Table) has been validated to ascertain the usefulness with an external cohort including European and Turkish studies; however, the predictive value of the Partin Table for Japanese men still needs to be established. Clinicopathological Research for Localized Prostate Cancer (CRPC), which is a disease registry to enable research into clinically localized prostate cancer cases accrued from 108 academic and community practices throughout Japan, validated the 2001 Partin Table and developed an original nomogram using a large series of Japanese patients.