Risk factors for and the prevalence of peripheral arterial disease and its relationship to carotid atherosclerosis: The Kyushu and Okinawa population study (KOPS)

Hachiro Ohnishi, Yasunori Sawayama, Norihiro Furusyo, Shinji Maeda, Shoji Hayashi, Jun Hayashi

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Aim: Peripheral arterial disease (PAD) is associated with cerebrovascular disease, ischemic heart disease, and other cardiovascular disease. We investigated the prevalence of and factors related to PAD to clarify the relationship between PAD and carotid atherosclerosis in a cross-sectional populationbased study. Methods: The study included 2,402 (900 males and 1,502 females; mean±SD = 64.9±10.9 years) of 3,862 residents of two Japanese rural areas who reported for a free health examination in 2005 or 2006. An ankle brachial index value ≤ 0.9 was considered to be PAD. The carotid artery intima-media thickness (CA-IMT) was measured by carotid ultrasound. Results: The prevalence of PAD was 1.71% (n= 41) of all participants. The risk factors independently associated with a significantly higher risk of PAD, identified by multivariate analysis, are as follows: For males, age, dyslipidemia, and CA-IMT, and for females, age, waist circumference, and dyslipidemia. Conclusion: The prevalence of PAD in Japan was confirmed to be lower than that of similar studies performed in other countries. PAD was strongly correlated with age and dyslipidemia in both sexes, carotid atherosclerosis in males, and abdominal fat in females.

Original languageEnglish
Pages (from-to)751-758
Number of pages8
JournalJournal of atherosclerosis and thrombosis
Volume17
Issue number7
DOIs
Publication statusPublished - Jan 1 2010

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Carotid Artery Diseases
Peripheral Arterial Disease
Population
Dyslipidemias
Carotid Intima-Media Thickness
Carotid Arteries
Cerebrovascular Disorders
Ankle Brachial Index
Abdominal Fat
Waist Circumference
Myocardial Ischemia
Japan
Cardiovascular Diseases
Multivariate Analysis
Cross-Sectional Studies
Ultrasonics
Health
Fats

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine
  • Biochemistry, medical

Cite this

Risk factors for and the prevalence of peripheral arterial disease and its relationship to carotid atherosclerosis : The Kyushu and Okinawa population study (KOPS). / Ohnishi, Hachiro; Sawayama, Yasunori; Furusyo, Norihiro; Maeda, Shinji; Hayashi, Shoji; Hayashi, Jun.

In: Journal of atherosclerosis and thrombosis, Vol. 17, No. 7, 01.01.2010, p. 751-758.

Research output: Contribution to journalArticle

Ohnishi, Hachiro ; Sawayama, Yasunori ; Furusyo, Norihiro ; Maeda, Shinji ; Hayashi, Shoji ; Hayashi, Jun. / Risk factors for and the prevalence of peripheral arterial disease and its relationship to carotid atherosclerosis : The Kyushu and Okinawa population study (KOPS). In: Journal of atherosclerosis and thrombosis. 2010 ; Vol. 17, No. 7. pp. 751-758.
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