Abstract
Background: To prevent hepatic failure after major hepatectomy, it is important to assess preoperative factors related to liver failure. Methods: We examined 80 patients who underwent right-sided hepatectomy. Hyperbilirubinemia, uncontrolled ascites, and prolonged postoperative hospital stay were defined as liver failure after hepatectomy, and these 3 factors were evaluated in relation to clinicopathological and surgical factors. Results In the 80 patients, hyperbilirubinemia was observed in 10 (12.7%) patients, uncontrolled ascites in 18 (22.5%) patients, and prolonged hospital stay after surgery in 39 (48.8%) patients. Multivariate analyses identified platelet count as a risk factor of hyperbilirubinemia, uncontrolled ascites, and prolonged postoperative hospital stay, and the ratio of remnant liver volume to body surface area (RLV/BSA ratio) as an additional risk factor of hyperbilirubinemia and prolonged postoperative hospital stay. Conclusions: Platelet count and RLV/BSA ratio are useful risk factors for prediction of liver failure after right-sided hepatectomy.
| Original language | English |
|---|---|
| Pages (from-to) | 374-379 |
| Number of pages | 6 |
| Journal | American Journal of Surgery |
| Volume | 206 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Sep 1 2013 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Surgery
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Risk factors of liver failure after right-sided hepatectomy. / Hirashita, Teijiro; Ohta, Masayuki; Iwashita, Yukio; Iwaki, Kentaro; Uchida, Hiroki; Yada, Kazuhiro; Matsumoto, Toshifumi; Kitano, Seigo.
In: American Journal of Surgery, Vol. 206, No. 3, 01.09.2013, p. 374-379.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Risk factors of liver failure after right-sided hepatectomy
AU - Hirashita, Teijiro
AU - Ohta, Masayuki
AU - Iwashita, Yukio
AU - Iwaki, Kentaro
AU - Uchida, Hiroki
AU - Yada, Kazuhiro
AU - Matsumoto, Toshifumi
AU - Kitano, Seigo
PY - 2013/9/1
Y1 - 2013/9/1
N2 - Background: To prevent hepatic failure after major hepatectomy, it is important to assess preoperative factors related to liver failure. Methods: We examined 80 patients who underwent right-sided hepatectomy. Hyperbilirubinemia, uncontrolled ascites, and prolonged postoperative hospital stay were defined as liver failure after hepatectomy, and these 3 factors were evaluated in relation to clinicopathological and surgical factors. Results In the 80 patients, hyperbilirubinemia was observed in 10 (12.7%) patients, uncontrolled ascites in 18 (22.5%) patients, and prolonged hospital stay after surgery in 39 (48.8%) patients. Multivariate analyses identified platelet count as a risk factor of hyperbilirubinemia, uncontrolled ascites, and prolonged postoperative hospital stay, and the ratio of remnant liver volume to body surface area (RLV/BSA ratio) as an additional risk factor of hyperbilirubinemia and prolonged postoperative hospital stay. Conclusions: Platelet count and RLV/BSA ratio are useful risk factors for prediction of liver failure after right-sided hepatectomy.
AB - Background: To prevent hepatic failure after major hepatectomy, it is important to assess preoperative factors related to liver failure. Methods: We examined 80 patients who underwent right-sided hepatectomy. Hyperbilirubinemia, uncontrolled ascites, and prolonged postoperative hospital stay were defined as liver failure after hepatectomy, and these 3 factors were evaluated in relation to clinicopathological and surgical factors. Results In the 80 patients, hyperbilirubinemia was observed in 10 (12.7%) patients, uncontrolled ascites in 18 (22.5%) patients, and prolonged hospital stay after surgery in 39 (48.8%) patients. Multivariate analyses identified platelet count as a risk factor of hyperbilirubinemia, uncontrolled ascites, and prolonged postoperative hospital stay, and the ratio of remnant liver volume to body surface area (RLV/BSA ratio) as an additional risk factor of hyperbilirubinemia and prolonged postoperative hospital stay. Conclusions: Platelet count and RLV/BSA ratio are useful risk factors for prediction of liver failure after right-sided hepatectomy.
UR - http://www.scopus.com/inward/record.url?scp=84882907124&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84882907124&partnerID=8YFLogxK
U2 - 10.1016/j.amjsurg.2012.12.013
DO - 10.1016/j.amjsurg.2012.12.013
M3 - Article
C2 - 23835210
AN - SCOPUS:84882907124
VL - 206
SP - 374
EP - 379
JO - American Journal of Surgery
JF - American Journal of Surgery
SN - 0002-9610
IS - 3
ER -