TY - JOUR
T1 - Risk factors of liver failure after right-sided hepatectomy
AU - Hirashita, Teijiro
AU - Ohta, Masayuki
AU - Iwashita, Yukio
AU - Iwaki, Kentaro
AU - Uchida, Hiroki
AU - Yada, Kazuhiro
AU - Matsumoto, Toshifumi
AU - Kitano, Seigo
PY - 2013/9
Y1 - 2013/9
N2 - Background: To prevent hepatic failure after major hepatectomy, it is important to assess preoperative factors related to liver failure. Methods: We examined 80 patients who underwent right-sided hepatectomy. Hyperbilirubinemia, uncontrolled ascites, and prolonged postoperative hospital stay were defined as liver failure after hepatectomy, and these 3 factors were evaluated in relation to clinicopathological and surgical factors. Results In the 80 patients, hyperbilirubinemia was observed in 10 (12.7%) patients, uncontrolled ascites in 18 (22.5%) patients, and prolonged hospital stay after surgery in 39 (48.8%) patients. Multivariate analyses identified platelet count as a risk factor of hyperbilirubinemia, uncontrolled ascites, and prolonged postoperative hospital stay, and the ratio of remnant liver volume to body surface area (RLV/BSA ratio) as an additional risk factor of hyperbilirubinemia and prolonged postoperative hospital stay. Conclusions: Platelet count and RLV/BSA ratio are useful risk factors for prediction of liver failure after right-sided hepatectomy.
AB - Background: To prevent hepatic failure after major hepatectomy, it is important to assess preoperative factors related to liver failure. Methods: We examined 80 patients who underwent right-sided hepatectomy. Hyperbilirubinemia, uncontrolled ascites, and prolonged postoperative hospital stay were defined as liver failure after hepatectomy, and these 3 factors were evaluated in relation to clinicopathological and surgical factors. Results In the 80 patients, hyperbilirubinemia was observed in 10 (12.7%) patients, uncontrolled ascites in 18 (22.5%) patients, and prolonged hospital stay after surgery in 39 (48.8%) patients. Multivariate analyses identified platelet count as a risk factor of hyperbilirubinemia, uncontrolled ascites, and prolonged postoperative hospital stay, and the ratio of remnant liver volume to body surface area (RLV/BSA ratio) as an additional risk factor of hyperbilirubinemia and prolonged postoperative hospital stay. Conclusions: Platelet count and RLV/BSA ratio are useful risk factors for prediction of liver failure after right-sided hepatectomy.
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U2 - 10.1016/j.amjsurg.2012.12.013
DO - 10.1016/j.amjsurg.2012.12.013
M3 - Article
C2 - 23835210
AN - SCOPUS:84882907124
VL - 206
SP - 374
EP - 379
JO - American Journal of Surgery
JF - American Journal of Surgery
SN - 0002-9610
IS - 3
ER -