Risk factors of liver failure after right-sided hepatectomy

Teijiro Hirashita, Masayuki Ohta, Yukio Iwashita, Kentaro Iwaki, Hiroki Uchida, Kazuhiro Yada, Toshifumi Matsumoto, Seigo Kitano

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

Background: To prevent hepatic failure after major hepatectomy, it is important to assess preoperative factors related to liver failure. Methods: We examined 80 patients who underwent right-sided hepatectomy. Hyperbilirubinemia, uncontrolled ascites, and prolonged postoperative hospital stay were defined as liver failure after hepatectomy, and these 3 factors were evaluated in relation to clinicopathological and surgical factors. Results In the 80 patients, hyperbilirubinemia was observed in 10 (12.7%) patients, uncontrolled ascites in 18 (22.5%) patients, and prolonged hospital stay after surgery in 39 (48.8%) patients. Multivariate analyses identified platelet count as a risk factor of hyperbilirubinemia, uncontrolled ascites, and prolonged postoperative hospital stay, and the ratio of remnant liver volume to body surface area (RLV/BSA ratio) as an additional risk factor of hyperbilirubinemia and prolonged postoperative hospital stay. Conclusions: Platelet count and RLV/BSA ratio are useful risk factors for prediction of liver failure after right-sided hepatectomy.

Original languageEnglish
Pages (from-to)374-379
Number of pages6
JournalAmerican Journal of Surgery
Volume206
Issue number3
DOIs
Publication statusPublished - Sep 2013

All Science Journal Classification (ASJC) codes

  • Surgery

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