Abstract
Ionic current sensing methods are useful tools for detecting sub- to several-micron scale particles such as bacteria. However, conventional commercially available ionic current sensing devices are not suitable for on-site measurement use because of inherent limitations on their robustness. Here, we proposed a portable robust ionic current sensor (Robust-ICS) using a bridge circuit that offers a high signal-to-noise (S/N) ratio by suppressing background current. Because the Robust-ICS can tolerate increased noise in current sensing, a simple, lightweight electromagnetic shield can be used and measurements under large electromagnetic noise conditions can be made. The weight of the device was lowered below 4 kg and outdoor particle detection measurements were completed successfully. Accuracy of size detection of Staphylococcus aureus (S. aureus) was equivalent to that obtained by SEM imaging.
| Original language | English |
|---|---|
| Pages (from-to) | 574-579 |
| Number of pages | 6 |
| Journal | ACS Sensors |
| Volume | 3 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Mar 23 2018 |
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All Science Journal Classification (ASJC) codes
- Bioengineering
- Instrumentation
- Process Chemistry and Technology
- Fluid Flow and Transfer Processes
Cite this
Robust Ionic Current Sensor for Bacterial Cell Size Detection. / Yasaki, Hirotoshi; Shimada, Taisuke; Yasui, Takao; Yanagida, Takeshi; Kaji, Noritada; Kanai, Masaki; Nagashima, Kazuki; Kawai, Tomoji; Baba, Yoshinobu.
In: ACS Sensors, Vol. 3, No. 3, 23.03.2018, p. 574-579.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Robust Ionic Current Sensor for Bacterial Cell Size Detection
AU - Yasaki, Hirotoshi
AU - Shimada, Taisuke
AU - Yasui, Takao
AU - Yanagida, Takeshi
AU - Kaji, Noritada
AU - Kanai, Masaki
AU - Nagashima, Kazuki
AU - Kawai, Tomoji
AU - Baba, Yoshinobu
PY - 2018/3/23
Y1 - 2018/3/23
N2 - Ionic current sensing methods are useful tools for detecting sub- to several-micron scale particles such as bacteria. However, conventional commercially available ionic current sensing devices are not suitable for on-site measurement use because of inherent limitations on their robustness. Here, we proposed a portable robust ionic current sensor (Robust-ICS) using a bridge circuit that offers a high signal-to-noise (S/N) ratio by suppressing background current. Because the Robust-ICS can tolerate increased noise in current sensing, a simple, lightweight electromagnetic shield can be used and measurements under large electromagnetic noise conditions can be made. The weight of the device was lowered below 4 kg and outdoor particle detection measurements were completed successfully. Accuracy of size detection of Staphylococcus aureus (S. aureus) was equivalent to that obtained by SEM imaging.
AB - Ionic current sensing methods are useful tools for detecting sub- to several-micron scale particles such as bacteria. However, conventional commercially available ionic current sensing devices are not suitable for on-site measurement use because of inherent limitations on their robustness. Here, we proposed a portable robust ionic current sensor (Robust-ICS) using a bridge circuit that offers a high signal-to-noise (S/N) ratio by suppressing background current. Because the Robust-ICS can tolerate increased noise in current sensing, a simple, lightweight electromagnetic shield can be used and measurements under large electromagnetic noise conditions can be made. The weight of the device was lowered below 4 kg and outdoor particle detection measurements were completed successfully. Accuracy of size detection of Staphylococcus aureus (S. aureus) was equivalent to that obtained by SEM imaging.
UR - http://www.scopus.com/inward/record.url?scp=85044400419&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85044400419&partnerID=8YFLogxK
U2 - 10.1021/acssensors.8b00045
DO - 10.1021/acssensors.8b00045
M3 - Article
C2 - 29420015
AN - SCOPUS:85044400419
VL - 3
SP - 574
EP - 579
JO - ACS Sensors
JF - ACS Sensors
SN - 2379-3694
IS - 3
ER -