Rotation vs. immobilization controversy in calix[6]arenes. Is 5,11,17,23,29,35-Hexa-tert-butyl-37,39,41-trimethoxy-38,40,42-tris(tert-butoxycarbonylmethoxy)calix[6]arene really immobilized?

Otsuka Hideyuki, Araki Koji, Sakaki Toru, Nakashima Kazuaki, Shinkai Seiji

Research output: Contribution to journalArticle

41 Citations (Scopus)


1H NMR spectral examinations revealed that the title compound, which was previously proposed to be conformationally-frozen, is not truly immobilized but the rate of the conformational change is just slower than that of the NMR time-scale.

Original languageEnglish
Pages (from-to)7275-7278
Number of pages4
JournalTetrahedron Letters
Issue number45
Publication statusPublished - Nov 5 1993


All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this