Saccharomyces cerevisiae cultured under aerobic and anaerobic conditions: Air-level oxygen stress and protection against stress

Shinji Ohmori, Yukinori Nawata, Kunihiko Kiyono, Hideaki Murata, Seiji Tsuboi, Mikiko Ikeda, Reiko Akagi, Ken-Ichirou Morohashi, Bun Ichiro Ono

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)

Abstract

Cells of Saccharomyces cerevisiae were grown aerobically and anaerobically, and levels of the protective compounds, cysteine and glutathione, and activities of defensive enzymes, catalase and superoxide dismutase, against an oxygen stress were determined and compared in both cells. Aerobiosis increased both the compounds and enzyme activities. The elevated synthesis of glutathione could be associated with the increased levels of cysteine which in its turn was found to be controlled by the oxygen-dependent activation of cystathionine β-synthase. Copyright (C) 1999 Elsevier Science B.V.

Original languageEnglish
Pages (from-to)587-594
Number of pages8
JournalBiochimica et Biophysica Acta - General Subjects
Volume1472
Issue number3
DOIs
Publication statusPublished - Nov 16 1999

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Biochemistry
  • Molecular Biology

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