TY - JOUR
T1 - Safety and efficacy of semichronic suprachoroidal transretinal stimulation with femtosecond laser-induced porosity and smooth-surface electrodes
AU - Terasawa, Yasuo
AU - Tashiro, Hiroyuki
AU - Nakano, Yukari
AU - Ohta, Jun
PY - 2018/1/1
Y1 - 2018/1/1
N2 - We have been developing a retinal prosthesis based on suprachoroidal transretinal stimulation (STS). From a practical viewpoint, it is essential to confirm the safety and effectiveness of continuous electrical stimulation to the retina. In this study, the electrical stimulation of a rabbit retina for 8 h a day was conducted for one month, and its safety and efficacy were evaluated by histological, electrophysiological, and electrochemical methods. Results suggested that one month of semichronic electrical stimulation by STS was safe and effective.
AB - We have been developing a retinal prosthesis based on suprachoroidal transretinal stimulation (STS). From a practical viewpoint, it is essential to confirm the safety and effectiveness of continuous electrical stimulation to the retina. In this study, the electrical stimulation of a rabbit retina for 8 h a day was conducted for one month, and its safety and efficacy were evaluated by histological, electrophysiological, and electrochemical methods. Results suggested that one month of semichronic electrical stimulation by STS was safe and effective.
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U2 - 10.18494/SAM.2018.1652
DO - 10.18494/SAM.2018.1652
M3 - Article
AN - SCOPUS:85041217256
VL - 30
SP - 235
EP - 249
JO - Sensors and Materials
JF - Sensors and Materials
SN - 0914-4935
IS - 2
ER -