Safety assessment of semichronic suprachoroidal electrical stimulation to rabbit retina

Yasuo Terasawa, Hiroyuki Tashiro, Yukari Nakano, Kouji Osawa, Motoki Ozawa

Research output: Chapter in Book/Report/Conference proceedingConference contribution

15 Citations (Scopus)

Abstract

Confirming safety of chronic electrical stimulation is of prime importance for the practical use of visual prostheses. Here we applied electrical stimulation to eyes of freely-moving rabbits eight hour per day for one month. Examinations including fundus photo, optical coherence tomography (OCT), electrically evoked potentials (EEPs) were performed before and after one-month stimulation to detect tissue damage. No adverse effect caused by electrical stimulation was observed in electrophysiological and histological evaluation. We also found that there was no sign of morphological and electrochemical degradation of stimulating electrodes.

Original languageEnglish
Title of host publication2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
Pages3567-3570
Number of pages4
DOIs
Publication statusPublished - Oct 31 2013
Event2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 - Osaka, Japan
Duration: Jul 3 2013Jul 7 2013

Publication series

NameProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
ISSN (Print)1557-170X

Other

Other2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
CountryJapan
CityOsaka
Period7/3/137/7/13

All Science Journal Classification (ASJC) codes

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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  • Cite this

    Terasawa, Y., Tashiro, H., Nakano, Y., Osawa, K., & Ozawa, M. (2013). Safety assessment of semichronic suprachoroidal electrical stimulation to rabbit retina. In 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 (pp. 3567-3570). [6610313] (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). https://doi.org/10.1109/EMBC.2013.6610313