Safety assessment of semichronic suprachoroidal electrical stimulation to rabbit retina

Yasuo Terasawa; Hiroyuki Tashiro; Yukari Nakano; Kouji Osawa; Motoki Ozawa

doi:10.1109/EMBC.2013.6610313

Safety assessment of semichronic suprachoroidal electrical stimulation to rabbit retina

Yasuo Terasawa, Hiroyuki Tashiro, Yukari Nakano, Kouji Osawa, Motoki Ozawa

Division of Medical Technology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

15 Citations (Scopus)

Abstract

Confirming safety of chronic electrical stimulation is of prime importance for the practical use of visual prostheses. Here we applied electrical stimulation to eyes of freely-moving rabbits eight hour per day for one month. Examinations including fundus photo, optical coherence tomography (OCT), electrically evoked potentials (EEPs) were performed before and after one-month stimulation to detect tissue damage. No adverse effect caused by electrical stimulation was observed in electrophysiological and histological evaluation. We also found that there was no sign of morphological and electrochemical degradation of stimulating electrodes.

Original language	English
Title of host publication	2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
Pages	3567-3570
Number of pages	4
DOIs	https://doi.org/10.1109/EMBC.2013.6610313
Publication status	Published - Oct 31 2013
Event	2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 - Osaka, Japan Duration: Jul 3 2013 → Jul 7 2013

Publication series

Name	Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
ISSN (Print)	1557-170X

Other

Other	2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
Country	Japan
City	Osaka
Period	7/3/13 → 7/7/13

All Science Journal Classification (ASJC) codes

Signal Processing
Biomedical Engineering
Computer Vision and Pattern Recognition
Health Informatics

Access to Document

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Cite this

Terasawa, Y., Tashiro, H., Nakano, Y., Osawa, K., & Ozawa, M. (2013). Safety assessment of semichronic suprachoroidal electrical stimulation to rabbit retina. In 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 (pp. 3567-3570). [6610313] (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). https://doi.org/10.1109/EMBC.2013.6610313

Safety assessment of semichronic suprachoroidal electrical stimulation to rabbit retina. / Terasawa, Yasuo; Tashiro, Hiroyuki; Nakano, Yukari; Osawa, Kouji; Ozawa, Motoki.

2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013. 2013. p. 3567-3570 6610313 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Terasawa, Y, Tashiro, H, Nakano, Y, Osawa, K & Ozawa, M 2013, Safety assessment of semichronic suprachoroidal electrical stimulation to rabbit retina. in 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013., 6610313, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, pp. 3567-3570, 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013, Osaka, Japan, 7/3/13. https://doi.org/10.1109/EMBC.2013.6610313

Terasawa Y, Tashiro H, Nakano Y, Osawa K, Ozawa M. Safety assessment of semichronic suprachoroidal electrical stimulation to rabbit retina. In 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013. 2013. p. 3567-3570. 6610313. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). https://doi.org/10.1109/EMBC.2013.6610313

Terasawa, Yasuo ; Tashiro, Hiroyuki ; Nakano, Yukari ; Osawa, Kouji ; Ozawa, Motoki. / Safety assessment of semichronic suprachoroidal electrical stimulation to rabbit retina. 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013. 2013. pp. 3567-3570 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

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