Abstract
Confirming safety of chronic electrical stimulation is of prime importance for the practical use of visual prostheses. Here we applied electrical stimulation to eyes of freely-moving rabbits eight hour per day for one month. Examinations including fundus photo, optical coherence tomography (OCT), electrically evoked potentials (EEPs) were performed before and after one-month stimulation to detect tissue damage. No adverse effect caused by electrical stimulation was observed in electrophysiological and histological evaluation. We also found that there was no sign of morphological and electrochemical degradation of stimulating electrodes.
| Original language | English |
|---|---|
| Title of host publication | 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 |
| Pages | 3567-3570 |
| Number of pages | 4 |
| DOIs | |
| Publication status | Published - Oct 31 2013 |
| Event | 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 - Osaka, Japan Duration: Jul 3 2013 → Jul 7 2013 |
Publication series
| Name | Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS |
|---|---|
| ISSN (Print) | 1557-170X |
Other
| Other | 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 |
|---|---|
| Country | Japan |
| City | Osaka |
| Period | 7/3/13 → 7/7/13 |
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All Science Journal Classification (ASJC) codes
- Signal Processing
- Biomedical Engineering
- Computer Vision and Pattern Recognition
- Health Informatics
Cite this
Safety assessment of semichronic suprachoroidal electrical stimulation to rabbit retina. / Terasawa, Yasuo; Tashiro, Hiroyuki; Nakano, Yukari; Osawa, Kouji; Ozawa, Motoki.
2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013. 2013. p. 3567-3570 6610313 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Safety assessment of semichronic suprachoroidal electrical stimulation to rabbit retina
AU - Terasawa, Yasuo
AU - Tashiro, Hiroyuki
AU - Nakano, Yukari
AU - Osawa, Kouji
AU - Ozawa, Motoki
PY - 2013/10/31
Y1 - 2013/10/31
N2 - Confirming safety of chronic electrical stimulation is of prime importance for the practical use of visual prostheses. Here we applied electrical stimulation to eyes of freely-moving rabbits eight hour per day for one month. Examinations including fundus photo, optical coherence tomography (OCT), electrically evoked potentials (EEPs) were performed before and after one-month stimulation to detect tissue damage. No adverse effect caused by electrical stimulation was observed in electrophysiological and histological evaluation. We also found that there was no sign of morphological and electrochemical degradation of stimulating electrodes.
AB - Confirming safety of chronic electrical stimulation is of prime importance for the practical use of visual prostheses. Here we applied electrical stimulation to eyes of freely-moving rabbits eight hour per day for one month. Examinations including fundus photo, optical coherence tomography (OCT), electrically evoked potentials (EEPs) were performed before and after one-month stimulation to detect tissue damage. No adverse effect caused by electrical stimulation was observed in electrophysiological and histological evaluation. We also found that there was no sign of morphological and electrochemical degradation of stimulating electrodes.
UR - http://www.scopus.com/inward/record.url?scp=84886498305&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84886498305&partnerID=8YFLogxK
U2 - 10.1109/EMBC.2013.6610313
DO - 10.1109/EMBC.2013.6610313
M3 - Conference contribution
C2 - 24110500
AN - SCOPUS:84886498305
SN - 9781457702167
T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
SP - 3567
EP - 3570
BT - 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
ER -