Safety assessment of semichronic suprachoroidal electrical stimulation to rabbit retina

Yasuo Terasawa, Hiroyuki Tashiro, Yukari Nakano, Kouji Osawa, Motoki Ozawa

Research output: Chapter in Book/Report/Conference proceedingConference contribution

14 Citations (Scopus)

Abstract

Confirming safety of chronic electrical stimulation is of prime importance for the practical use of visual prostheses. Here we applied electrical stimulation to eyes of freely-moving rabbits eight hour per day for one month. Examinations including fundus photo, optical coherence tomography (OCT), electrically evoked potentials (EEPs) were performed before and after one-month stimulation to detect tissue damage. No adverse effect caused by electrical stimulation was observed in electrophysiological and histological evaluation. We also found that there was no sign of morphological and electrochemical degradation of stimulating electrodes.

Original languageEnglish
Title of host publication2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
Pages3567-3570
Number of pages4
DOIs
Publication statusPublished - Oct 31 2013
Event2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 - Osaka, Japan
Duration: Jul 3 2013Jul 7 2013

Publication series

NameProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
ISSN (Print)1557-170X

Other

Other2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
CountryJapan
CityOsaka
Period7/3/137/7/13

Fingerprint

Optical tomography
Bioelectric potentials
Prosthetics
Electric Stimulation
Retina
Tissue
Rabbits
Safety
Degradation
Electrodes
Visual Prosthesis
Optical Coherence Tomography
Evoked Potentials

All Science Journal Classification (ASJC) codes

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

Cite this

Terasawa, Y., Tashiro, H., Nakano, Y., Osawa, K., & Ozawa, M. (2013). Safety assessment of semichronic suprachoroidal electrical stimulation to rabbit retina. In 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 (pp. 3567-3570). [6610313] (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). https://doi.org/10.1109/EMBC.2013.6610313

Safety assessment of semichronic suprachoroidal electrical stimulation to rabbit retina. / Terasawa, Yasuo; Tashiro, Hiroyuki; Nakano, Yukari; Osawa, Kouji; Ozawa, Motoki.

2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013. 2013. p. 3567-3570 6610313 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Terasawa, Y, Tashiro, H, Nakano, Y, Osawa, K & Ozawa, M 2013, Safety assessment of semichronic suprachoroidal electrical stimulation to rabbit retina. in 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013., 6610313, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, pp. 3567-3570, 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013, Osaka, Japan, 7/3/13. https://doi.org/10.1109/EMBC.2013.6610313
Terasawa Y, Tashiro H, Nakano Y, Osawa K, Ozawa M. Safety assessment of semichronic suprachoroidal electrical stimulation to rabbit retina. In 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013. 2013. p. 3567-3570. 6610313. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). https://doi.org/10.1109/EMBC.2013.6610313
Terasawa, Yasuo ; Tashiro, Hiroyuki ; Nakano, Yukari ; Osawa, Kouji ; Ozawa, Motoki. / Safety assessment of semichronic suprachoroidal electrical stimulation to rabbit retina. 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013. 2013. pp. 3567-3570 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).
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