Safety study of skin care cosmetics for sensitive skin in patients with a history of contact dermatitis and/or atopic dermatitis

Miki Tanioka, Yoshiki Miyachi, Setsuya Aiba, Katsuko Kikuchi, Osamu Ishikawa, Yayoi Nagai, Tadashi Terui, Hidenao Shimizu, Masatoshi Ito, Hiromi Kantoh, Kayoko Matsunaga, Akiko Yagami, Ichiro Katayama, Shigeki Inui, Masamitsu Ishii, Hiromi Kobayashi, Atsuko Kato, Masutaka Furue, Noriko Fukiwake, Syuhei ImayamaYumiko Suzuki

Research output: Contribution to journalArticle

Abstract

We carried out a four-week study in patients with a history of contact dermatitis and/or atopic dermatitis in order to assess the safety of new sensitive-skin cosmetics containing hyaluronic acid. We found adverse skin reactions in 9.6% of the subjects who used the lotion (enriched type), in 6.7% of the subjects who used the lotion (light type), in 8.2% of the subjects who used the emulsion, and in 6.5% of the subjects who used the cream. These adverse skin reactions were slight or moderate, and there was no severe reaction. All subjects presented with dryness of the face at week 0 on clinical examination. More than 85% of the subjects exhibited improvement of facial skin dryness at 4 weeks. The satisfaction index for skin condition, obtained by using a visual analog scale, showed a notable improvement after the study. The results indicate that these skin care cosmetics are safe and useful for patients with contact dermatitis and/or atopic dermatitis.

Original languageEnglish
Pages (from-to)263-273
Number of pages11
JournalSkin Research
Volume7
Issue number2
Publication statusPublished - Apr 1 2008

All Science Journal Classification (ASJC) codes

  • Dermatology
  • Infectious Diseases

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    Tanioka, M., Miyachi, Y., Aiba, S., Kikuchi, K., Ishikawa, O., Nagai, Y., Terui, T., Shimizu, H., Ito, M., Kantoh, H., Matsunaga, K., Yagami, A., Katayama, I., Inui, S., Ishii, M., Kobayashi, H., Kato, A., Furue, M., Fukiwake, N., ... Suzuki, Y. (2008). Safety study of skin care cosmetics for sensitive skin in patients with a history of contact dermatitis and/or atopic dermatitis. Skin Research, 7(2), 263-273.