Salvage esophagectomy after definitive chemoradiotherapy for synchronous double cancers of the esophagus and head-and-neck

R. Yoshida, M. Morita, K. Ando, T. Masuda, H. Saeki, E. Oki, N. Sadanaga, T. Nakashima, Y. Kakeji, Y. Maehara

Research output: Contribution to journalArticle

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Abstract

Head-and-neck cancer is frequently associated with esophageal cancer. Because the operative procedures for these synchronous double cancers are too invasive, definitive chemoradiotherapy tends to be applied as an initial treatment. A salvage esophagectomy for either recurrent or residual disease after definitive chemoradiotherapy in patients with such double cancer has never been reported. We reviewed 21 patients with esophageal cancer who underwent a salvage esophagectomy after definitive chemoradiotherapy. Among them, the treatment course of five patients who underwent a salvage esophagectomy for patients with synchronous double cancers of the esophagus and head-and-neck region was analyzed. Because head-and-neck cancer was well controlled after chemoradiotherapy in all five patients, a salvage esophagectomy was indicated for either recurrent or residual esophageal cancer after definitive chemoradiotherapy. Anastomotic leakage developed in four patients; however, no other complications including pulmonary complications were recognized. All of them were discharged to home and three of them are still alive without any recurrence for 20-43 months. A salvage esophagectomy should be considered as a treatment option for either recurrent or residual esophageal cancer with well-controlled head-and neck cancer after definitive chemoradiotherapy when complete resection of the esophagus is expected.

Original languageEnglish
Pages (from-to)59-63
Number of pages5
JournalDiseases of the Esophagus
Volume23
Issue number1
DOIs
Publication statusPublished - Jan 1 2010

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Esophagectomy
Chemoradiotherapy
Esophageal Neoplasms
Head and Neck Neoplasms
Residual Neoplasm
Anastomotic Leak
Operative Surgical Procedures
Esophagus
Neoplasms
Therapeutics
Recurrence
Lung

All Science Journal Classification (ASJC) codes

  • Gastroenterology

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Salvage esophagectomy after definitive chemoradiotherapy for synchronous double cancers of the esophagus and head-and-neck. / Yoshida, R.; Morita, M.; Ando, K.; Masuda, T.; Saeki, H.; Oki, E.; Sadanaga, N.; Nakashima, T.; Kakeji, Y.; Maehara, Y.

In: Diseases of the Esophagus, Vol. 23, No. 1, 01.01.2010, p. 59-63.

Research output: Contribution to journalArticle

Yoshida, R. ; Morita, M. ; Ando, K. ; Masuda, T. ; Saeki, H. ; Oki, E. ; Sadanaga, N. ; Nakashima, T. ; Kakeji, Y. ; Maehara, Y. / Salvage esophagectomy after definitive chemoradiotherapy for synchronous double cancers of the esophagus and head-and-neck. In: Diseases of the Esophagus. 2010 ; Vol. 23, No. 1. pp. 59-63.
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