Sappanin-type homoisoflavonoids from Sansevieria trifasciata Prain

Billy T. Tchegnitegni, Rémy B. Teponno, Chiaki Tanaka, Adeyemi F. Gabriel, Léon A. Tapondjou, Tomofumi Miyamoto

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Abstract Two new sappanin-type homoisoflavonoids, (3R)-7-hydroxy-8-methoxy-3′,4′-methylenedioxyhomoisoflavanone (trifasciatine A) 1 and (3R)-3,7-dihydroxy-8-methoxy-3′,4′-methylenedioxyhomoisoflavanone (trifasciatine B) 2 were isolated as minor components from the EtOAc soluble fraction of the methanol extract of Sansevieria trifasciata collected in Cameroon together with the known 1-(stearoyl)-glycerol 3 and spirosta-5,25(27)-dien-1β,3β-diol-1-O-α-l-rhamnopyranosyl-(1 → 2)-α-l-arabinopyranoside 4. Their structures were elucidated mainly by extensive spectroscopic analysis (1D and 2D NMR) and HRESIMS. Compounds 1 and 2 were screened for their antiproliferative activity on HeLa cells and no significant effect was observed when compare to 5-FU (fluorouracil) used as positive control.

Original languageEnglish
Article number936
Pages (from-to)262-266
Number of pages5
JournalPhytochemistry Letters
Volume12
DOIs
Publication statusPublished - Jun 16 2015

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Sansevieria
Sansevieria trifasciata
fluorouracil
glycols
Cameroon
Fluorouracil
glycerol
methanol
Spectroscopic analysis
extracts
HeLa Cells
Glycerol
Methanol
Nuclear magnetic resonance
cells

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Biochemistry
  • Agronomy and Crop Science
  • Plant Science

Cite this

Sappanin-type homoisoflavonoids from Sansevieria trifasciata Prain. / Tchegnitegni, Billy T.; Teponno, Rémy B.; Tanaka, Chiaki; Gabriel, Adeyemi F.; Tapondjou, Léon A.; Miyamoto, Tomofumi.

In: Phytochemistry Letters, Vol. 12, 936, 16.06.2015, p. 262-266.

Research output: Contribution to journalArticle

Tchegnitegni, Billy T. ; Teponno, Rémy B. ; Tanaka, Chiaki ; Gabriel, Adeyemi F. ; Tapondjou, Léon A. ; Miyamoto, Tomofumi. / Sappanin-type homoisoflavonoids from Sansevieria trifasciata Prain. In: Phytochemistry Letters. 2015 ; Vol. 12. pp. 262-266.
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