Schizophrenia

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Despite the high prevalence of schizophrenia, which is a devastating mental disorder, the etiology and pathophysiology of this disease are still unclear. Magnetoencephalography (MEG) has a high spatial and temporal resolution and has been used to make important contributions to schizophrenia research. In this chapter, we review MEG studies of schizophrenia, with an emphasis on event-related responses and neural oscillations. Published MEG studies suggest that patients with schizophrenia have neurophysiological deficits from the early phase of sensory processing (i.e., M50, M100, mismatch negativity) in auditory perception. Moreover, schizophrenia patients may have altered neural oscillations, and abnormalities of auditory steady-state responses to 40 Hz click stimuli are repeatedly reported. Because this research can be conducted in living schizophrenia patients, these biological results are highly valuable for understanding the etiology and pathophysiology of the disorder. As advanced medical technology becomes increasingly globally available, the clinical application of MEG to schizophrenia treatment may be imminent.

Original languageEnglish
Title of host publicationClinical Applications of Magnetoencephalography
PublisherSpringer Japan
Pages275-288
Number of pages14
ISBN (Electronic)9784431557296
ISBN (Print)9784431557289
DOIs
Publication statusPublished - Jan 1 2016

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Schizophrenia
Magnetoencephalography
Auditory Perception
Research
Mental Disorders
Technology

All Science Journal Classification (ASJC) codes

  • Medicine(all)
  • Neuroscience(all)

Cite this

Onitsuka, T., & Hirano, S. (2016). Schizophrenia. In Clinical Applications of Magnetoencephalography (pp. 275-288). Springer Japan. https://doi.org/10.1007/978-4-431-55729-6_14

Schizophrenia. / Onitsuka, Toshiaki; Hirano, Shogo.

Clinical Applications of Magnetoencephalography. Springer Japan, 2016. p. 275-288.

Research output: Chapter in Book/Report/Conference proceedingChapter

Onitsuka, T & Hirano, S 2016, Schizophrenia. in Clinical Applications of Magnetoencephalography. Springer Japan, pp. 275-288. https://doi.org/10.1007/978-4-431-55729-6_14
Onitsuka T, Hirano S. Schizophrenia. In Clinical Applications of Magnetoencephalography. Springer Japan. 2016. p. 275-288 https://doi.org/10.1007/978-4-431-55729-6_14
Onitsuka, Toshiaki ; Hirano, Shogo. / Schizophrenia. Clinical Applications of Magnetoencephalography. Springer Japan, 2016. pp. 275-288
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