TY - JOUR
T1 - Scoliosis in patients with multiple hereditary exostoses
AU - Matsumoto, Yoshihiro
AU - Matsumoto, Kazu
AU - Harimaya, Katsumi
AU - Okada, Seiji
AU - Doi, Toshio
AU - Iwamoto, Yukihide
N1 - Publisher Copyright:
© 2015, Springer-Verlag Berlin Heidelberg.
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2015/7/27
Y1 - 2015/7/27
N2 - Purpose: To investigate the prevalence of and to identify independent predictors associated with scoliosis in patients with multiple hereditary exostoses (MHE). Methods: Fifty patients with MHE were clinically examined, and the diagnosis of scoliosis was made based on radiographs. To classify disease severity, three classes based on the presence of deformities and functional limitations were defined. Significant independent predictors of scoliosis in MHE were statistically analyzed. Results: Scoliosis was present in 36 patients (MHE-scoliosis) (72 %). In the MHE-scoliosis group, the mean primary curve was 15.3° ± 5.7° (range 10°–34°) and the mean minor curve was 10.6° ± 7° (range 6°–32°). Left curve was predominant (72 %), and the apex was located in the thoracolumbar or lumbar spine in 64 % of patients. Univariable and multivariable analyses confirmed that MHE severity was a significant predictor of moderate scoliosis (≥20°). Conclusions: Our study confirmed that scoliosis is a common feature of MHE and disease severity is a predictor of moderate scoliosis (≥20°).
AB - Purpose: To investigate the prevalence of and to identify independent predictors associated with scoliosis in patients with multiple hereditary exostoses (MHE). Methods: Fifty patients with MHE were clinically examined, and the diagnosis of scoliosis was made based on radiographs. To classify disease severity, three classes based on the presence of deformities and functional limitations were defined. Significant independent predictors of scoliosis in MHE were statistically analyzed. Results: Scoliosis was present in 36 patients (MHE-scoliosis) (72 %). In the MHE-scoliosis group, the mean primary curve was 15.3° ± 5.7° (range 10°–34°) and the mean minor curve was 10.6° ± 7° (range 6°–32°). Left curve was predominant (72 %), and the apex was located in the thoracolumbar or lumbar spine in 64 % of patients. Univariable and multivariable analyses confirmed that MHE severity was a significant predictor of moderate scoliosis (≥20°). Conclusions: Our study confirmed that scoliosis is a common feature of MHE and disease severity is a predictor of moderate scoliosis (≥20°).
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U2 - 10.1007/s00586-015-3883-4
DO - 10.1007/s00586-015-3883-4
M3 - Article
C2 - 25794701
AN - SCOPUS:84933180155
VL - 24
SP - 1568
EP - 1573
JO - European Spine Journal
JF - European Spine Journal
SN - 0940-6719
IS - 7
ER -