Secondary degeneration of the substantia nigra and corticospinal tract after hemorrhagic middle cerebral artery infarction: Diffusion-weighted MR findings

Toshibumi Kinoshita, Toshio Moritani, David A. Shrier, Henry Z. Wang, Akio Hiwatashi, Yuji Numaguchi, Per Lennart A. Westesson

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Middle cerebral artery (MCA) infarction involving the striatum can cause secondary degeneration of the substantia nigra and corticospinal tract. We present a patient with subacute hemorrhagic MCA infarction in whom diffusion-weighted MR images showed high signal intensity in the ipsilateral substantia nigra and corticospinal tract. A corresponding apparent diffusion coefficient map revealed a uniformly decreased signal in the same area. This represents secondary degeneration and should not be mistaken for other pathological conditions, such as a new infarction.

Original languageEnglish
Pages (from-to)175-178
Number of pages4
JournalMagnetic Resonance in Medical Sciences
Issue number3
Publication statusPublished - Dec 1 2002
Externally publishedYes


All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

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