Selection of peptides with the recognition of stereoregular PMMA from phage library

Toshiki Sawada, Hisao Matsuno, Teruhiko Matsubara, Toshinori Sato, Tatsuki Kitayama, Takeshi Serizawa

Research output: Contribution to conferencePaperpeer-review


To identify peptides with affinity selective for stereoregular isotactic poly(methyl methacrylate) (it-PMMA), phage library displaying a heptamer random peptide was used. After five rounds of biopanning, several phage clones with high specific affinity to it-PMMA were selected. As a result of DNA sequencing, nine kinds of it-PMMA binding phage clones were isolated. Binding affinity and specificity of these phage clones were quantitatively investigated by enzyme-linked immunosorbent assay. These clones not only bound to it-PMMA greater than phage library, but showed the specific binding to it-PMMA rather than syndiotactic and atactic PMMAs.

Original languageEnglish
Number of pages1
Publication statusPublished - Dec 1 2005
Externally publishedYes
Event54th SPSJ Annual Meeting 2005 - Yokohama, Japan
Duration: May 25 2005May 27 2005


Other54th SPSJ Annual Meeting 2005

All Science Journal Classification (ASJC) codes

  • Engineering(all)


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