Selective oxidation of alcohol-d1to aldehyde-d1using MnO2

Hironori Okamura, Yoko Yasuno, Atsushi Nakayama, Katsushi Kumadaki, Kohei Kitsuwa, Keita Ozawa, Yusaku Tamura, Yuki Yamamoto, Tetsuro Shinada

Research output: Contribution to journalArticlepeer-review

Abstract

The selective oxidation of alcohol-d1to prepare aldehyde-d1was newly developed by means of NaBD4reduction/activated MnO2oxidation. Various aldehyde-d1derivatives including aromatic and unsaturated aldehyde-d1can be prepared with a high deuterium incorporation ratio (up to 98% D). Halogens (chloride, bromide, and iodide), alkene, alkyne, ester, nitro, and cyano groups in the substrates are tolerated under the mild conditions.

Original languageEnglish
Pages (from-to)28530-28534
Number of pages5
JournalRSC Advances
Volume11
Issue number46
DOIs
Publication statusPublished - Aug 16 2021
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Chemical Engineering(all)

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