Stereospecific recognition of substrate molecules for certain chiral carboxylic acids is achieved by a noncovalent receptor system based on acid-base interactions of amino groups in the host system with the carboxylic acids. Enantioselectivity in the binding process is caused by secondary interactions with a chiral platform that preorganizes the amino functionalities (see scheme).
|Number of pages||6|
|Journal||Angewandte Chemie - International Edition|
|Publication status||Published - Jun 3 2002|
All Science Journal Classification (ASJC) codes