Self-assembled receptors for enantioselective recognition of chiral carboxylic acids in a highly cooperative manner

Tsutomu Ishi-I, Mercedes Crego-Calama, Peter Timmerman, David N. Reinhoudt, Seiji Shinkai

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Abstract

Stereospecific recognition of substrate molecules for certain chiral carboxylic acids is achieved by a noncovalent receptor system based on acid-base interactions of amino groups in the host system with the carboxylic acids. Enantioselectivity in the binding process is caused by secondary interactions with a chiral platform that preorganizes the amino functionalities (see scheme).

Original languageEnglish
Pages (from-to)1924-1929
Number of pages6
JournalAngewandte Chemie - International Edition
Volume41
Issue number11
DOIs
Publication statusPublished - Jun 3 2002
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)

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