Self-assembled synthetic viral capsids from a 24-mer viral peptide fragment

Kazunori Matsuura, Kenta Watanabe, Tsubasa Matsuzaki, Kazuo Sakurai, Nobuo Kimizuka

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Abstract

Assemble a virus: A chemical strategy to de novo design "tailor-made" viruslike nanocapsules was developed (see picture). 24-mer β-annulus peptides of the tomato bushy stunt virus (TBSV) spontaneously self-assemble into hollow nanocapsules with a size of 30-50 nm. The hollow structure of the assemblies was clearly revealed by small-angle X-ray scattering (SAXS).

Original languageEnglish
Pages (from-to)9662-9665
Number of pages4
JournalAngewandte Chemie - International Edition
Volume49
Issue number50
DOIs
Publication statusPublished - Dec 10 2010

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All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)

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