Self-assembled synthetic viral capsids from a 24-mer viral peptide fragment

Kazunori Matsuura, Kenta Watanabe, Tsubasa Matsuzaki, Kazuo Sakurai, Nobuo Kimizuka

    Research output: Contribution to journalArticlepeer-review

    78 Citations (Scopus)

    Abstract

    Assemble a virus: A chemical strategy to de novo design "tailor-made" viruslike nanocapsules was developed (see picture). 24-mer β-annulus peptides of the tomato bushy stunt virus (TBSV) spontaneously self-assemble into hollow nanocapsules with a size of 30-50 nm. The hollow structure of the assemblies was clearly revealed by small-angle X-ray scattering (SAXS).

    Original languageEnglish
    Pages (from-to)9662-9665
    Number of pages4
    JournalAngewandte Chemie - International Edition
    Volume49
    Issue number50
    DOIs
    Publication statusPublished - Dec 10 2010

    All Science Journal Classification (ASJC) codes

    • Catalysis
    • Chemistry(all)

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