Abstract
In this study, we report fluorescent organic nanoprobes with intense blue, green, and orange-red emissions prepared by self-assembling three carbazole derivatives into nanorods/nanoparticles. The three compounds consist of two or four electron-donating carbazole groups linked to a central dicyanobenzene electron acceptor. Steric hindrance from the carbazole groups leads to noncoplanar 3D molecular structures favorable to fluorescence in the solid state, while the donor-acceptor structures endow the molecules with good two-photon excited emission properties. The fluorescent organic nanoprobes exhibit good water dispersibility, low cytotoxicity, superior resistance against photodegradation and photobleaching. Both one- and two-photon fluorescent imaging were shown in the A549 cell line. Two-photon fluorescence imaging with the fluorescent probes was demonstrated to be more effective in visualizing and distinguishing cellular details compared to conventional one-photon fluorescence imaging.
| Original language | English |
|---|---|
| Pages (from-to) | 11355-11365 |
| Number of pages | 11 |
| Journal | ACS Applied Materials and Interfaces |
| Volume | 8 |
| Issue number | 18 |
| DOIs | |
| Publication status | Published - May 11 2016 |
Fingerprint
All Science Journal Classification (ASJC) codes
- Materials Science(all)
Cite this
Self-Assembly of Electron Donor-Acceptor-Based Carbazole Derivatives : Novel Fluorescent Organic Nanoprobes for Both One- and Two-Photon Cellular Imaging. / Zhang, Jinfeng; Chen, Wencheng; Kalytchuk, Sergii; Li, King Fai; Chen, Rui; Adachi, Chihaya; Chen, Zhan; Rogach, Andrey L.; Zhu, Guangyu; Yu, Peter K.N.; Zhang, Wenjun; Cheah, Kok Wai; Zhang, Xiaohong; Lee, Chun Sing.
In: ACS Applied Materials and Interfaces, Vol. 8, No. 18, 11.05.2016, p. 11355-11365.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Self-Assembly of Electron Donor-Acceptor-Based Carbazole Derivatives
T2 - Novel Fluorescent Organic Nanoprobes for Both One- and Two-Photon Cellular Imaging
AU - Zhang, Jinfeng
AU - Chen, Wencheng
AU - Kalytchuk, Sergii
AU - Li, King Fai
AU - Chen, Rui
AU - Adachi, Chihaya
AU - Chen, Zhan
AU - Rogach, Andrey L.
AU - Zhu, Guangyu
AU - Yu, Peter K.N.
AU - Zhang, Wenjun
AU - Cheah, Kok Wai
AU - Zhang, Xiaohong
AU - Lee, Chun Sing
PY - 2016/5/11
Y1 - 2016/5/11
N2 - In this study, we report fluorescent organic nanoprobes with intense blue, green, and orange-red emissions prepared by self-assembling three carbazole derivatives into nanorods/nanoparticles. The three compounds consist of two or four electron-donating carbazole groups linked to a central dicyanobenzene electron acceptor. Steric hindrance from the carbazole groups leads to noncoplanar 3D molecular structures favorable to fluorescence in the solid state, while the donor-acceptor structures endow the molecules with good two-photon excited emission properties. The fluorescent organic nanoprobes exhibit good water dispersibility, low cytotoxicity, superior resistance against photodegradation and photobleaching. Both one- and two-photon fluorescent imaging were shown in the A549 cell line. Two-photon fluorescence imaging with the fluorescent probes was demonstrated to be more effective in visualizing and distinguishing cellular details compared to conventional one-photon fluorescence imaging.
AB - In this study, we report fluorescent organic nanoprobes with intense blue, green, and orange-red emissions prepared by self-assembling three carbazole derivatives into nanorods/nanoparticles. The three compounds consist of two or four electron-donating carbazole groups linked to a central dicyanobenzene electron acceptor. Steric hindrance from the carbazole groups leads to noncoplanar 3D molecular structures favorable to fluorescence in the solid state, while the donor-acceptor structures endow the molecules with good two-photon excited emission properties. The fluorescent organic nanoprobes exhibit good water dispersibility, low cytotoxicity, superior resistance against photodegradation and photobleaching. Both one- and two-photon fluorescent imaging were shown in the A549 cell line. Two-photon fluorescence imaging with the fluorescent probes was demonstrated to be more effective in visualizing and distinguishing cellular details compared to conventional one-photon fluorescence imaging.
UR - http://www.scopus.com/inward/record.url?scp=84974777191&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84974777191&partnerID=8YFLogxK
U2 - 10.1021/acsami.6b03259
DO - 10.1021/acsami.6b03259
M3 - Article
C2 - 27097920
AN - SCOPUS:84974777191
VL - 8
SP - 11355
EP - 11365
JO - ACS applied materials & interfaces
JF - ACS applied materials & interfaces
SN - 1944-8244
IS - 18
ER -