Sensing of oligopeptides using alternatively-deposited gold nanorods for surface-assisted laser desorption/ionization time-of-flight mass spectrometry

Masanori Fujii, Naotoshi Nakashima, Yasuro Niidome

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Gold nanorods (NRs) were fixed on an ITO plate and used for the Surface-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (SALDI-MS) of oligopeptides (angiotensin I). The SALDI-MS measurements had a high sensitivity to the angiotensin on the ITO plate on which isolated NRs were deposited. Angiotensin molecules in a very diluted solution (1 × 10 -11 M) could be detected at m/z = 1297 with a good signal/noise ratio (S/N = 18). In contrast, alternatively deposited NR an ITO plate, which present broad surface plasmon bands, was found to be inactive for SALDI measurements.

Original languageEnglish
Title of host publicationGels and Biomedical Materials
Pages145-149
Number of pages5
DOIs
Publication statusPublished - Aug 20 2012
Event2011 MRS Fall Meeting - Boston, MA, United States
Duration: Nov 28 2011Dec 2 2011

Publication series

NameMaterials Research Society Symposium Proceedings
Volume1418
ISSN (Print)0272-9172

Other

Other2011 MRS Fall Meeting
CountryUnited States
CityBoston, MA
Period11/28/1112/2/11

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

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    Fujii, M., Nakashima, N., & Niidome, Y. (2012). Sensing of oligopeptides using alternatively-deposited gold nanorods for surface-assisted laser desorption/ionization time-of-flight mass spectrometry. In Gels and Biomedical Materials (pp. 145-149). (Materials Research Society Symposium Proceedings; Vol. 1418). https://doi.org/10.1557/opl.2012.379