Sensing of oligopeptides using alternatively-deposited gold nanorods for surface-assisted laser desorption/ionization time-of-flight mass spectrometry

Masanori Fujii, Naotoshi Nakashima, Yasuro Niidome

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Gold nanorods (NRs) were fixed on an ITO plate and used for the Surface-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (SALDI-MS) of oligopeptides (angiotensin I). The SALDI-MS measurements had a high sensitivity to the angiotensin on the ITO plate on which isolated NRs were deposited. Angiotensin molecules in a very diluted solution (1 × 10 -11 M) could be detected at m/z = 1297 with a good signal/noise ratio (S/N = 18). In contrast, alternatively deposited NR an ITO plate, which present broad surface plasmon bands, was found to be inactive for SALDI measurements.

Original languageEnglish
Title of host publicationGels and Biomedical Materials
Pages145-149
Number of pages5
DOIs
Publication statusPublished - Aug 20 2012
Event2011 MRS Fall Meeting - Boston, MA, United States
Duration: Nov 28 2011Dec 2 2011

Publication series

NameMaterials Research Society Symposium Proceedings
Volume1418
ISSN (Print)0272-9172

Other

Other2011 MRS Fall Meeting
CountryUnited States
CityBoston, MA
Period11/28/1112/2/11

Fingerprint

angiotensins
Oligopeptides
ITO (semiconductors)
Nanorods
Gold
nanorods
Ionization
Mass spectrometry
Desorption
mass spectroscopy
desorption
Angiotensins
gold
ionization
Lasers
lasers
Angiotensin I
Molecules
sensitivity
molecules

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

Cite this

Fujii, M., Nakashima, N., & Niidome, Y. (2012). Sensing of oligopeptides using alternatively-deposited gold nanorods for surface-assisted laser desorption/ionization time-of-flight mass spectrometry. In Gels and Biomedical Materials (pp. 145-149). (Materials Research Society Symposium Proceedings; Vol. 1418). https://doi.org/10.1557/opl.2012.379

Sensing of oligopeptides using alternatively-deposited gold nanorods for surface-assisted laser desorption/ionization time-of-flight mass spectrometry. / Fujii, Masanori; Nakashima, Naotoshi; Niidome, Yasuro.

Gels and Biomedical Materials. 2012. p. 145-149 (Materials Research Society Symposium Proceedings; Vol. 1418).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Fujii, M, Nakashima, N & Niidome, Y 2012, Sensing of oligopeptides using alternatively-deposited gold nanorods for surface-assisted laser desorption/ionization time-of-flight mass spectrometry. in Gels and Biomedical Materials. Materials Research Society Symposium Proceedings, vol. 1418, pp. 145-149, 2011 MRS Fall Meeting, Boston, MA, United States, 11/28/11. https://doi.org/10.1557/opl.2012.379
Fujii M, Nakashima N, Niidome Y. Sensing of oligopeptides using alternatively-deposited gold nanorods for surface-assisted laser desorption/ionization time-of-flight mass spectrometry. In Gels and Biomedical Materials. 2012. p. 145-149. (Materials Research Society Symposium Proceedings). https://doi.org/10.1557/opl.2012.379
Fujii, Masanori ; Nakashima, Naotoshi ; Niidome, Yasuro. / Sensing of oligopeptides using alternatively-deposited gold nanorods for surface-assisted laser desorption/ionization time-of-flight mass spectrometry. Gels and Biomedical Materials. 2012. pp. 145-149 (Materials Research Society Symposium Proceedings).
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