Sensing of oligopeptides using alternatively-deposited gold nanorods for surface-assisted laser desorption/ionization time-of-flight mass spectrometry

Masanori Fujii, Naotoshi Nakashima, Yasuro Niidome

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    Gold nanorods (NRs) were fixed on an ITO plate and used for the Surface-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (SALDI-MS) of oligopeptides (angiotensin I). The SALDI-MS measurements had a high sensitivity to the angiotensin on the ITO plate on which isolated NRs were deposited. Angiotensin molecules in a very diluted solution (1 × 10 -11 M) could be detected at m/z = 1297 with a good signal/noise ratio (S/N = 18). In contrast, alternatively deposited NR an ITO plate, which present broad surface plasmon bands, was found to be inactive for SALDI measurements.

    Original languageEnglish
    Title of host publicationGels and Biomedical Materials
    Pages145-149
    Number of pages5
    DOIs
    Publication statusPublished - 2012
    Event2011 MRS Fall Meeting - Boston, MA, United States
    Duration: Nov 28 2011Dec 2 2011

    Publication series

    NameMaterials Research Society Symposium Proceedings
    Volume1418
    ISSN (Print)0272-9172

    Other

    Other2011 MRS Fall Meeting
    Country/TerritoryUnited States
    CityBoston, MA
    Period11/28/1112/2/11

    All Science Journal Classification (ASJC) codes

    • Materials Science(all)
    • Condensed Matter Physics
    • Mechanics of Materials
    • Mechanical Engineering

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