Separation of naphthalenesulfonate isomers by capillary zone electrophoresis using macrocyclic polyamines as additive for running solution

Koji Takahashi, Tomonori Nakagawa, Toshihiko Imato

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    12 Citations (Scopus)

    Abstract

    The separation of naphthalenesulfonate (NS) isomers has been successfully performed by capillary zone electrophoresis using macrocyclic polyamines, such as [9]aneN3 and [14]aneN4, as an additive to the running solution. Although group separation between naphthalenemonosulfonates (mono-NSs) and naphthalenedisulfonates (di-NSs) was achieved, the separation between mono-NS isomers, 1-NS and 2-NS, and the separation among di-NS isomers, 1,5-NS, 1,6-NS, 2,6-NS and 2,7-NS, could not be achieved using a hydrochloric acid solution (pH 2.0) as the running solution. The addition of [14]aneN4 to the running solution (pH 2.0) gave good separation, not only between mono-NSs and di-NSs but also among their NS isomers. The sequence of elution time increased in the order 2,6-NS < 2,7-NS < 1,6-NS < 1,5-NS < 2-NS < 1-NS. The sequence of elution time indicates that the interaction of the NSs with [14]aneN4 increases in the order 2,6-NS < 2,7-NS < 1,6-NS < 1,5-NS for the di-NS isomers and 2-NS < 1-NS for the mono-NS isomers. A similar sequence of elution time was obtained when [9]aneN3 was used as the additive, although the separations between the 1,5- and 1,6-NS isomers and 1- and 2-NS isomers was not complete. The elution sequence and the separation efficiency among the NS isomers are discussed with reference to the molecular structures of the macrocyclic polyamines and the NS isomers.

    Original languageEnglish
    Pages (from-to)221-224
    Number of pages4
    JournalAnalytical Communications
    Volume35
    Issue number7
    DOIs
    Publication statusPublished - Jan 1 1998

    All Science Journal Classification (ASJC) codes

    • Analytical Chemistry

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