Separation of naphthalenesulfonate isomers by capillary zone electrophoresis using macrocyclic polyamines as additive for running solution

Koji Takahashi, Tomonori Nakagawa, Toshihiko Imato

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The separation of naphthalenesulfonate (NS) isomers has been successfully performed by capillary zone electrophoresis using macrocyclic polyamines, such as [9]aneN3 and [14]aneN4, as an additive to the running solution. Although group separation between naphthalenemonosulfonates (mono-NSs) and naphthalenedisulfonates (di-NSs) was achieved, the separation between mono-NS isomers, 1-NS and 2-NS, and the separation among di-NS isomers, 1,5-NS, 1,6-NS, 2,6-NS and 2,7-NS, could not be achieved using a hydrochloric acid solution (pH 2.0) as the running solution. The addition of [14]aneN4 to the running solution (pH 2.0) gave good separation, not only between mono-NSs and di-NSs but also among their NS isomers. The sequence of elution time increased in the order 2,6-NS < 2,7-NS < 1,6-NS < 1,5-NS < 2-NS < 1-NS. The sequence of elution time indicates that the interaction of the NSs with [14]aneN4 increases in the order 2,6-NS < 2,7-NS < 1,6-NS < 1,5-NS for the di-NS isomers and 2-NS < 1-NS for the mono-NS isomers. A similar sequence of elution time was obtained when [9]aneN3 was used as the additive, although the separations between the 1,5- and 1,6-NS isomers and 1- and 2-NS isomers was not complete. The elution sequence and the separation efficiency among the NS isomers are discussed with reference to the molecular structures of the macrocyclic polyamines and the NS isomers.

Original languageEnglish
Pages (from-to)221-224
Number of pages4
JournalAnalytical Communications
Volume35
Issue number7
DOIs
Publication statusPublished - Jan 1 1998

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry

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