TY - JOUR
T1 - Serum glucose, cholesterol and blood pressure levels in Japanese type 1 and 2 diabetic patients
T2 - BioBank Japan
AU - Biobank Japan Cooperative Hospital Group
AU - Yokomichi, Hiroshi
AU - Nagai, Akiko
AU - Hirata, Makoto
AU - Kiyohara, Yutaka
AU - Muto, Kaori
AU - Ninomiya, Toshiharu
AU - Matsuda, Koichi
AU - Kamatani, Yoichiro
AU - Tamakoshi, Akiko
AU - Kubo, Michiaki
AU - Nakamura, Yusuke
AU - Yamagata, Zentaro
AU - Matsubayashi, Sunao
AU - Harada, Hiromasa
AU - Misumi, Kazuo
AU - Komi, Rieko
AU - Minami, Shiro
AU - Sugihara, Hitoshi
AU - Emoto, Naoya
AU - Kanazawa, Akio
AU - Suzuki, Yusuke
AU - Hiratsuka, Yoshimune
AU - Asai, Satoshi
AU - Moriyama, Mitsuhiko
AU - Takahashi, Yasuo
AU - Fujioka, Tomoaki
AU - Obara, Wataru
AU - Mori, Seijiro
AU - Ito, Hideki
AU - Nagayama, Satoshi
AU - Miki, Yoshio
AU - Masumoto, Akihide
AU - Yamada, Akira
AU - Nishizawa, Yasuko
AU - Kodama, Ken
AU - Ugi, Satoshi
AU - Maegawa, Hiroshi
AU - Koretsune, Yukihiro
AU - Taki, Hideki
AU - Osawa, Takeshi
N1 - Funding Information:
This work was supported by funds from the Tailor-Made Medical Treatment Program with the BioBank Japan Project from Japan Agency for Medical Research and Development (AMED) since April 2015 and the Ministry of Education, Culture, Sports, Science, and Technology (MEXT) from April 2003 to March 2015. This work was also supported by MEXT [KAKENHI grant number: JP15K08730 and JP15K15221].
Publisher Copyright:
© 2017 The Authors.
PY - 2017
Y1 - 2017
N2 - Background: Evidence of characteristics of Japanese patients with diabetes from a large-scale population is necessary. Few studies have compared glycaemic controls, complications and comorbidities between type 1 and 2 diabetic patients. This paper focuses on illustrating a clinical picture of Japanese diabetic patients and comparing glycaemic control and prognoses between type 1 and 2 diabetes using multiinstitutional data. Methods: The BioBank Japan Project enrolled adult type 1 and 2 diabetic patients between fiscal years 2003 and 2007. We have presented characteristics, controls of serum glucose, cholesterol and blood pressure, prevalence of complications and comorbidities and survival curves. We have also shown glycaemic controls according to various individual profiles of diabetic patients. Results: A total of 558 type 1 diabetic patients and 30,834 type 2 diabetic patients participated in this study. The mean glycated haemoglobin A1c was higher in type 1 diabetes than in type 2 diabetes. In the type 1 diabetic patients, the glycated haemoglobin A1c had no consistent trend according to age and body mass index. The KaplaneMeier estimates represented a longer survival time from baseline with type 1 diabetes than with type 2 diabetes. Compared with type 1 diabetic patients, type 2 diabetic patients had double the prevalence of macrovascular complications. Conclusions: This work has revealed detailed plasma glucose levels of type 1 and 2 diabetic patients according to age, body mass index, blood pressure, serum cholesterol levels and smoking and drinking habits. Our data have also shown that the prognosis is worse for type 2 diabetes than for type 1 diabetes in Japan.
AB - Background: Evidence of characteristics of Japanese patients with diabetes from a large-scale population is necessary. Few studies have compared glycaemic controls, complications and comorbidities between type 1 and 2 diabetic patients. This paper focuses on illustrating a clinical picture of Japanese diabetic patients and comparing glycaemic control and prognoses between type 1 and 2 diabetes using multiinstitutional data. Methods: The BioBank Japan Project enrolled adult type 1 and 2 diabetic patients between fiscal years 2003 and 2007. We have presented characteristics, controls of serum glucose, cholesterol and blood pressure, prevalence of complications and comorbidities and survival curves. We have also shown glycaemic controls according to various individual profiles of diabetic patients. Results: A total of 558 type 1 diabetic patients and 30,834 type 2 diabetic patients participated in this study. The mean glycated haemoglobin A1c was higher in type 1 diabetes than in type 2 diabetes. In the type 1 diabetic patients, the glycated haemoglobin A1c had no consistent trend according to age and body mass index. The KaplaneMeier estimates represented a longer survival time from baseline with type 1 diabetes than with type 2 diabetes. Compared with type 1 diabetic patients, type 2 diabetic patients had double the prevalence of macrovascular complications. Conclusions: This work has revealed detailed plasma glucose levels of type 1 and 2 diabetic patients according to age, body mass index, blood pressure, serum cholesterol levels and smoking and drinking habits. Our data have also shown that the prognosis is worse for type 2 diabetes than for type 1 diabetes in Japan.
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U2 - 10.1016/j.je.2016.12.013
DO - 10.1016/j.je.2016.12.013
M3 - Article
C2 - 28162891
AN - SCOPUS:85016395269
SN - 0917-5040
VL - 27
SP - S92-S97
JO - Journal of Epidemiology
JF - Journal of Epidemiology
IS - 3
ER -
