Severe hyponatremia in a case of severe spinal injury: Sequential examination of factors affecting water-electrolyte balance

Takanori Inamura, Hiroshi Ueno, Tateyoshi Nishiyama, Masashi Nakamura, Kiyonobu Ikezaki, Satoshi Inoha, Akira Nakamizo, Toshiyuki Amano, Masashi Fukui

Research output: Contribution to journalArticlepeer-review

Abstract

Although hyponatremia has been known to occur in patients with severe spinal cord injury with highly incidence, its mechanism has not been understood well. We examined a 64-year-old patient with severe hyponatremia after spinal cord injury by sequential measuring of the factors affecting water-electrolyte balance, such as antidiuretic hormone, renin, angiotensin II, atrial natriuretic peptide, and brain natriuretic peptide. The patient showed severe hypotension due to dysfunction of the sympathetic nerve. The hyponatremia gradually resolved with the improvement of sympathetic nerve function. According to those results, the sympathetic nerve dysfunction was thought to correlate with the hyponatremia, and it was suggested that the unknown sympathetic regulation of water-electrolyte balance existed.

Original languageEnglish
Pages (from-to)23-27
Number of pages5
JournalBrain and Nerve
Volume54
Issue number1
Publication statusPublished - 2002

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

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