Severe left ventricular dysfunction in a patient with primary Sjögren’s syndrome

Sachiko Takaoka, Masanori Higuchi, Keita Odashiro, Shigeru Yoshizawa, Takahiko Horiuchi, Yoshiyuki Niho

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A 43-year-old woman was admitted to our hospital for evaluation of shortness of breath and palpitation on exertion. She had a 20-year history of dry mouth and a 10-year history of recurrent pneumonia. She had been diagnosed as having primary Sjögren’s syndrome with interstitial pneumonia at 42 years of age. On admission, cardiac ultrasonography revealed reduced left ventricular systolic function. Complications that would elicit cardiac manifestations such as viral myocarditis, amyloidosis, sarcoidosis, and ischemic heart disease, were excluded. Oral corticosteroid therapy was effective for alleviating symptoms. In this patient, it appears that primary Sjögren’s syndrome is involved in the reduced left ventricular systolic function.

Original languageEnglish
Pages (from-to)199-205
Number of pages7
JournalJapanese Journal of Clinical Immunology
Issue number3
Publication statusPublished - Jan 1 1997


All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology

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