Severe thrombocytopenia caused by digitoxin intoxication in a patient with heart failure associated with Sjogren's syndrome

Takashi Haro, Eimei Shimoike, Takahiko Horiuchi, Toru Maruyama, Yoshiyuki Niho

Research output: Contribution to journalArticle

3 Citations (Scopus)


Congestive heart failure (CHF) related to Sjogren's syndrome is extremely rare. This report concerns a patient who presented with CHF and severe thrombocytopenia (5,000/μl). Serum concentrations of K, Mg and digitoxin were 3.2 mmol/L, 1.4 mg/L and 57.2 ng/ml, respectively. Digitoxin intoxication was evident, seemingly evoked by hypokalemia, hypomagnesemia; hepatorenal dysfunction and hypothyroidism. The severe thrombocytopenia was considered to have been caused by this intoxication, as it disappeared soon after the digitoxin was discontinued and potassium was supplemented.

Original languageEnglish
Pages (from-to)309-311
Number of pages3
Issue number4
Publication statusPublished - Apr 1 2000


All Science Journal Classification (ASJC) codes

  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this