Short- and long-term results of the Frey procedure for chronic pancreatitis

Junji Ueda, Yoshihiro Miyasaka, Ohtsuka Takao, Shunichi Takahata, Masao Tanaka

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Background The aim of this study was to determine the short- and long-term results of the Frey procedure for chronic pancreatitis. Methods From November 1998 to December 2013, 41 patients underwent the Frey procedure for painful chronic pancreatitis at Kyushu University Hospital. The short- and long-term results of the Frey procedure including mortality, morbidity, pain relief, weight gain and pancreatic endocrine function were analyzed. The long-term results were analyzed in 29 patients who had been followed-up for more than 12 months. The long-term follow-up rate was 85%. Results There was no mortality. Early postoperative complications occurred in seven patients (17%), including pancreatic fistula in four (10%, International Study Group of Pancreatic Fistula ISGPF grade B) and hemorrhage in three (7%). Long-term relief of abdominal pain was achieved in 90% (26/29) of cases. One patient developed relapse of inflammation of the head of pancreas during the follow-up period, necessitating pylorus-resecting pancreatoduodenectomy. Only two patients (7%) developed new-onset diabetes mellitus after the Frey procedure during the follow-up period. Conclusions The Frey procedure for painful chronic pancreatitis may be safe and pancreatic endocrine function is preserved. Complete decompression of the pancreatic ducts in the head of pancreas and full length drainage of the main pancreatic duct from the head of pancreas to the tail may be important in the Frey procedure to prevent recurrence of acute inflammation.

Original languageEnglish
Pages (from-to)211-216
Number of pages6
JournalJournal of Hepato-Biliary-Pancreatic Sciences
Volume22
Issue number3
DOIs
Publication statusPublished - Mar 1 2015

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Chronic Pancreatitis
Pancreatic Fistula
Pancreas
Pancreatic Ducts
Inflammation
Recurrence
Pancreaticoduodenectomy
Mortality
Pylorus
Decompression
Abdominal Pain
Weight Gain
Drainage
Diabetes Mellitus
Hemorrhage
Morbidity
Pain

All Science Journal Classification (ASJC) codes

  • Surgery
  • Hepatology

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Short- and long-term results of the Frey procedure for chronic pancreatitis. / Ueda, Junji; Miyasaka, Yoshihiro; Takao, Ohtsuka; Takahata, Shunichi; Tanaka, Masao.

In: Journal of Hepato-Biliary-Pancreatic Sciences, Vol. 22, No. 3, 01.03.2015, p. 211-216.

Research output: Contribution to journalArticle

Ueda, Junji ; Miyasaka, Yoshihiro ; Takao, Ohtsuka ; Takahata, Shunichi ; Tanaka, Masao. / Short- and long-term results of the Frey procedure for chronic pancreatitis. In: Journal of Hepato-Biliary-Pancreatic Sciences. 2015 ; Vol. 22, No. 3. pp. 211-216.
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abstract = "Background The aim of this study was to determine the short- and long-term results of the Frey procedure for chronic pancreatitis. Methods From November 1998 to December 2013, 41 patients underwent the Frey procedure for painful chronic pancreatitis at Kyushu University Hospital. The short- and long-term results of the Frey procedure including mortality, morbidity, pain relief, weight gain and pancreatic endocrine function were analyzed. The long-term results were analyzed in 29 patients who had been followed-up for more than 12 months. The long-term follow-up rate was 85{\%}. Results There was no mortality. Early postoperative complications occurred in seven patients (17{\%}), including pancreatic fistula in four (10{\%}, International Study Group of Pancreatic Fistula ISGPF grade B) and hemorrhage in three (7{\%}). Long-term relief of abdominal pain was achieved in 90{\%} (26/29) of cases. One patient developed relapse of inflammation of the head of pancreas during the follow-up period, necessitating pylorus-resecting pancreatoduodenectomy. Only two patients (7{\%}) developed new-onset diabetes mellitus after the Frey procedure during the follow-up period. Conclusions The Frey procedure for painful chronic pancreatitis may be safe and pancreatic endocrine function is preserved. Complete decompression of the pancreatic ducts in the head of pancreas and full length drainage of the main pancreatic duct from the head of pancreas to the tail may be important in the Frey procedure to prevent recurrence of acute inflammation.",
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