Signet ring cell adenocarcinoma of the lung with an EML4-ALK fusion gene mimicking mucinous (colloid) adenocarcinoma: A case report

Taro Ohba; Kenji Sugio; Takuro Kometani; Masafumi Yamaguchi; Motoharu Hamatake; Kaname Nosaki; Hiroaki Takeoka; Hiromoto Kitajima; Fumihiko Hirai; Takashi Seto; Kenichi Taguchi; Kenichi Nishiyama; Yoshitaka Shida; Yukito Ichinose

doi:10.1016/j.lungcan.2011.05.016

Signet ring cell adenocarcinoma of the lung with an EML4-ALK fusion gene mimicking mucinous (colloid) adenocarcinoma: A case report

Taro Ohba, Kenji Sugio, Takuro Kometani, Masafumi Yamaguchi, Motoharu Hamatake, Kaname Nosaki, Hiroaki Takeoka, Hiromoto Kitajima, Fumihiko Hirai, Takashi Seto, Kenichi Taguchi, Kenichi Nishiyama, Yoshitaka Shida, Yukito Ichinose

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

We herein report a case of signet ring cell adenocarcinoma of the lung with an EML4-ALK fusion gene mimicking mucinous (colloid) adenocarcinoma. A 79-year-old female presented with a pulmonary tumor located in the right lower lobe measuring 21. mm in size. A right lower lobectomy was performed. The postoperative pathological examination revealed signet ring cell carcinoma with abundant mucin pools, and a multiplex RT-PCR analysis revealed the variant 2 inversion of the EML4-ALK gene.

Original language	English
Pages (from-to)	375-378
Number of pages	4
Journal	Lung Cancer
Volume	73
Issue number	3
DOIs	https://doi.org/10.1016/j.lungcan.2011.05.016
Publication status	Published - Sep 2011

All Science Journal Classification (ASJC) codes

Oncology
Pulmonary and Respiratory Medicine
Cancer Research

Access to Document

10.1016/j.lungcan.2011.05.016

Fingerprint Dive into the research topics of 'Signet ring cell adenocarcinoma of the lung with an EML4-ALK fusion gene mimicking mucinous (colloid) adenocarcinoma: A case report'. Together they form a unique fingerprint.

Cite this

Ohba, T., Sugio, K., Kometani, T., Yamaguchi, M., Hamatake, M., Nosaki, K., Takeoka, H., Kitajima, H., Hirai, F., Seto, T., Taguchi, K., Nishiyama, K., Shida, Y., & Ichinose, Y. (2011). Signet ring cell adenocarcinoma of the lung with an EML4-ALK fusion gene mimicking mucinous (colloid) adenocarcinoma: A case report. Lung Cancer, 73(3), 375-378. https://doi.org/10.1016/j.lungcan.2011.05.016

Signet ring cell adenocarcinoma of the lung with an EML4-ALK fusion gene mimicking mucinous (colloid) adenocarcinoma : A case report. / Ohba, Taro; Sugio, Kenji; Kometani, Takuro; Yamaguchi, Masafumi; Hamatake, Motoharu; Nosaki, Kaname; Takeoka, Hiroaki; Kitajima, Hiromoto; Hirai, Fumihiko; Seto, Takashi; Taguchi, Kenichi; Nishiyama, Kenichi; Shida, Yoshitaka; Ichinose, Yukito.

In: Lung Cancer, Vol. 73, No. 3, 09.2011, p. 375-378.

Research output: Contribution to journal › Article › peer-review

Ohba, T, Sugio, K, Kometani, T, Yamaguchi, M, Hamatake, M, Nosaki, K, Takeoka, H, Kitajima, H, Hirai, F, Seto, T, Taguchi, K, Nishiyama, K, Shida, Y & Ichinose, Y 2011, 'Signet ring cell adenocarcinoma of the lung with an EML4-ALK fusion gene mimicking mucinous (colloid) adenocarcinoma: A case report', Lung Cancer, vol. 73, no. 3, pp. 375-378. https://doi.org/10.1016/j.lungcan.2011.05.016

Ohba, Taro ; Sugio, Kenji ; Kometani, Takuro ; Yamaguchi, Masafumi ; Hamatake, Motoharu ; Nosaki, Kaname ; Takeoka, Hiroaki ; Kitajima, Hiromoto ; Hirai, Fumihiko ; Seto, Takashi ; Taguchi, Kenichi ; Nishiyama, Kenichi ; Shida, Yoshitaka ; Ichinose, Yukito. / Signet ring cell adenocarcinoma of the lung with an EML4-ALK fusion gene mimicking mucinous (colloid) adenocarcinoma : A case report. In: Lung Cancer. 2011 ; Vol. 73, No. 3. pp. 375-378.

@article{5bbcee384f024864a3803c383a13713a,

title = "Signet ring cell adenocarcinoma of the lung with an EML4-ALK fusion gene mimicking mucinous (colloid) adenocarcinoma: A case report",

abstract = "We herein report a case of signet ring cell adenocarcinoma of the lung with an EML4-ALK fusion gene mimicking mucinous (colloid) adenocarcinoma. A 79-year-old female presented with a pulmonary tumor located in the right lower lobe measuring 21. mm in size. A right lower lobectomy was performed. The postoperative pathological examination revealed signet ring cell carcinoma with abundant mucin pools, and a multiplex RT-PCR analysis revealed the variant 2 inversion of the EML4-ALK gene.",

author = "Taro Ohba and Kenji Sugio and Takuro Kometani and Masafumi Yamaguchi and Motoharu Hamatake and Kaname Nosaki and Hiroaki Takeoka and Hiromoto Kitajima and Fumihiko Hirai and Takashi Seto and Kenichi Taguchi and Kenichi Nishiyama and Yoshitaka Shida and Yukito Ichinose",

year = "2011",

month = sep,

doi = "10.1016/j.lungcan.2011.05.016",

language = "English",

volume = "73",

pages = "375--378",

journal = "Lung Cancer",

issn = "0169-5002",

publisher = "Elsevier Ireland Ltd",

number = "3",

}

TY - JOUR

T1 - Signet ring cell adenocarcinoma of the lung with an EML4-ALK fusion gene mimicking mucinous (colloid) adenocarcinoma

T2 - A case report

AU - Ohba, Taro

AU - Sugio, Kenji

AU - Kometani, Takuro

AU - Yamaguchi, Masafumi

AU - Hamatake, Motoharu

AU - Nosaki, Kaname

AU - Takeoka, Hiroaki

AU - Kitajima, Hiromoto

AU - Hirai, Fumihiko

AU - Seto, Takashi

AU - Taguchi, Kenichi

AU - Nishiyama, Kenichi

AU - Shida, Yoshitaka

AU - Ichinose, Yukito

PY - 2011/9

Y1 - 2011/9

N2 - We herein report a case of signet ring cell adenocarcinoma of the lung with an EML4-ALK fusion gene mimicking mucinous (colloid) adenocarcinoma. A 79-year-old female presented with a pulmonary tumor located in the right lower lobe measuring 21. mm in size. A right lower lobectomy was performed. The postoperative pathological examination revealed signet ring cell carcinoma with abundant mucin pools, and a multiplex RT-PCR analysis revealed the variant 2 inversion of the EML4-ALK gene.

AB - We herein report a case of signet ring cell adenocarcinoma of the lung with an EML4-ALK fusion gene mimicking mucinous (colloid) adenocarcinoma. A 79-year-old female presented with a pulmonary tumor located in the right lower lobe measuring 21. mm in size. A right lower lobectomy was performed. The postoperative pathological examination revealed signet ring cell carcinoma with abundant mucin pools, and a multiplex RT-PCR analysis revealed the variant 2 inversion of the EML4-ALK gene.

UR - http://www.scopus.com/inward/record.url?scp=79960894408&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79960894408&partnerID=8YFLogxK

U2 - 10.1016/j.lungcan.2011.05.016

DO - 10.1016/j.lungcan.2011.05.016

M3 - Article

C2 - 21719143

AN - SCOPUS:79960894408

VL - 73

SP - 375

EP - 378

JO - Lung Cancer

JF - Lung Cancer

SN - 0169-5002

IS - 3

ER -