Signet ring cell adenocarcinoma of the lung with an EML4-ALK fusion gene mimicking mucinous (colloid) adenocarcinoma: A case report

Taro Ohba, Kenji Sugio, Takuro Kometani, Masafumi Yamaguchi, Motoharu Hamatake, Kaname Nosaki, Hiroaki Takeoka, Hiromoto Kitajima, Fumihiko Hirai, Takashi Seto, Kenichi Taguchi, Kenichi Nishiyama, Yoshitaka Shida, Yukito Ichinose

Research output: Contribution to journalArticle

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Abstract

We herein report a case of signet ring cell adenocarcinoma of the lung with an EML4-ALK fusion gene mimicking mucinous (colloid) adenocarcinoma. A 79-year-old female presented with a pulmonary tumor located in the right lower lobe measuring 21. mm in size. A right lower lobectomy was performed. The postoperative pathological examination revealed signet ring cell carcinoma with abundant mucin pools, and a multiplex RT-PCR analysis revealed the variant 2 inversion of the EML4-ALK gene.

Original languageEnglish
Pages (from-to)375-378
Number of pages4
JournalLung Cancer
Volume73
Issue number3
DOIs
Publication statusPublished - Sep 1 2011

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Signet Ring Cell Carcinoma
Mucinous Adenocarcinoma
Gene Fusion
Multiplex Polymerase Chain Reaction
Colloids
Mucins
Lung
Genes
Neoplasms
Adenocarcinoma of lung

All Science Journal Classification (ASJC) codes

  • Oncology
  • Pulmonary and Respiratory Medicine
  • Cancer Research

Cite this

Signet ring cell adenocarcinoma of the lung with an EML4-ALK fusion gene mimicking mucinous (colloid) adenocarcinoma : A case report. / Ohba, Taro; Sugio, Kenji; Kometani, Takuro; Yamaguchi, Masafumi; Hamatake, Motoharu; Nosaki, Kaname; Takeoka, Hiroaki; Kitajima, Hiromoto; Hirai, Fumihiko; Seto, Takashi; Taguchi, Kenichi; Nishiyama, Kenichi; Shida, Yoshitaka; Ichinose, Yukito.

In: Lung Cancer, Vol. 73, No. 3, 01.09.2011, p. 375-378.

Research output: Contribution to journalArticle

Ohba, T, Sugio, K, Kometani, T, Yamaguchi, M, Hamatake, M, Nosaki, K, Takeoka, H, Kitajima, H, Hirai, F, Seto, T, Taguchi, K, Nishiyama, K, Shida, Y & Ichinose, Y 2011, 'Signet ring cell adenocarcinoma of the lung with an EML4-ALK fusion gene mimicking mucinous (colloid) adenocarcinoma: A case report', Lung Cancer, vol. 73, no. 3, pp. 375-378. https://doi.org/10.1016/j.lungcan.2011.05.016
Ohba, Taro ; Sugio, Kenji ; Kometani, Takuro ; Yamaguchi, Masafumi ; Hamatake, Motoharu ; Nosaki, Kaname ; Takeoka, Hiroaki ; Kitajima, Hiromoto ; Hirai, Fumihiko ; Seto, Takashi ; Taguchi, Kenichi ; Nishiyama, Kenichi ; Shida, Yoshitaka ; Ichinose, Yukito. / Signet ring cell adenocarcinoma of the lung with an EML4-ALK fusion gene mimicking mucinous (colloid) adenocarcinoma : A case report. In: Lung Cancer. 2011 ; Vol. 73, No. 3. pp. 375-378.
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