Significance of mesenteric lymphadenopathy after pancreaticoduodenectomy for periampullary carcinomas: Evaluation with serial MDCT studies

Kousei Ishigami, Kengo Yoshimitsu, Hiroyuki Irie, Tsuyoshi Tajima, Yoshiki Asayama, Masakazu Hirakawa, Daisuke Kakihara, Yoshiyuki Shioyama, Yunosuke Nishihara, Koji Yamaguchi, Hiroshi Honda

Research output: Contribution to journalArticle

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Abstract

Objective: To evaluate the significance of mesenteric lymphadenopathy arising after pancreaticoduodenectomy (PD) for periampullary carcinomas. Materials and methods: Serial multidetector CT (MDCT) studies in 44 patients after PD for periampullary carcinomas (Group A) were retrospectively reviewed, the incidence and interval changes of mesenteric lymphadenopathy were evaluated, and comparisons were made with 21 patients who underwent PD for benign diseases (Group B). Results: In Group A, mesenteric lymphadenopathy was seen in 31 of 44 (70.5%) patients. The short axis diameter of the largest lymph node ranged from 6.2 to 11.5 mm (mean ± S.D.: 8.6 ± 1.4 mm), and the short-axis-to-long-axis (S/L) ratio ranged from 0.46 to 0.99 (mean ± S.D.: 0.69 ± 0.12). Six of the 31 (19.4%) mesenteric lymphadenopathy cases showed interval increases in size on follow-up studies, and three cases showed new development of mesenteric lymphadenopathy: all of these nine cases had concurrent recurrence in the mesenteric root. In Group B, 11 (52.4%) had mesenteric lymphadenopathy. The short axis diameter of the largest lymph node ranged from 5.6 to 10.9 mm (mean ± S.D.: 8.0 ± 1.9 mm) and the S/L ratio ranged from 0.48 to 0.93 (mean ± S.D.: 0.67 ± 0.12). Differences in the incidence, short axis diameter and S/L ratio were not significant between Groups A and B (p = 0.154, 0.271 and 0.654, respectively). Conclusion: Mesenetric lymphadenopathy after PD less likely reflects recurrence. Lymph node metastasis may be suggested only when coexisting recurrent mass is found in the proximal mesenteric root.

Original languageEnglish
Pages (from-to)491-498
Number of pages8
JournalEuropean Journal of Radiology
Volume61
Issue number3
DOIs
Publication statusPublished - Mar 1 2007

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Pancreaticoduodenectomy
Carcinoma
Lymph Nodes
Recurrence
Incidence
Lymphadenopathy
Neoplasm Metastasis

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

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Significance of mesenteric lymphadenopathy after pancreaticoduodenectomy for periampullary carcinomas : Evaluation with serial MDCT studies. / Ishigami, Kousei; Yoshimitsu, Kengo; Irie, Hiroyuki; Tajima, Tsuyoshi; Asayama, Yoshiki; Hirakawa, Masakazu; Kakihara, Daisuke; Shioyama, Yoshiyuki; Nishihara, Yunosuke; Yamaguchi, Koji; Honda, Hiroshi.

In: European Journal of Radiology, Vol. 61, No. 3, 01.03.2007, p. 491-498.

Research output: Contribution to journalArticle

Ishigami, Kousei ; Yoshimitsu, Kengo ; Irie, Hiroyuki ; Tajima, Tsuyoshi ; Asayama, Yoshiki ; Hirakawa, Masakazu ; Kakihara, Daisuke ; Shioyama, Yoshiyuki ; Nishihara, Yunosuke ; Yamaguchi, Koji ; Honda, Hiroshi. / Significance of mesenteric lymphadenopathy after pancreaticoduodenectomy for periampullary carcinomas : Evaluation with serial MDCT studies. In: European Journal of Radiology. 2007 ; Vol. 61, No. 3. pp. 491-498.
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abstract = "Objective: To evaluate the significance of mesenteric lymphadenopathy arising after pancreaticoduodenectomy (PD) for periampullary carcinomas. Materials and methods: Serial multidetector CT (MDCT) studies in 44 patients after PD for periampullary carcinomas (Group A) were retrospectively reviewed, the incidence and interval changes of mesenteric lymphadenopathy were evaluated, and comparisons were made with 21 patients who underwent PD for benign diseases (Group B). Results: In Group A, mesenteric lymphadenopathy was seen in 31 of 44 (70.5{\%}) patients. The short axis diameter of the largest lymph node ranged from 6.2 to 11.5 mm (mean ± S.D.: 8.6 ± 1.4 mm), and the short-axis-to-long-axis (S/L) ratio ranged from 0.46 to 0.99 (mean ± S.D.: 0.69 ± 0.12). Six of the 31 (19.4{\%}) mesenteric lymphadenopathy cases showed interval increases in size on follow-up studies, and three cases showed new development of mesenteric lymphadenopathy: all of these nine cases had concurrent recurrence in the mesenteric root. In Group B, 11 (52.4{\%}) had mesenteric lymphadenopathy. The short axis diameter of the largest lymph node ranged from 5.6 to 10.9 mm (mean ± S.D.: 8.0 ± 1.9 mm) and the S/L ratio ranged from 0.48 to 0.93 (mean ± S.D.: 0.67 ± 0.12). Differences in the incidence, short axis diameter and S/L ratio were not significant between Groups A and B (p = 0.154, 0.271 and 0.654, respectively). Conclusion: Mesenetric lymphadenopathy after PD less likely reflects recurrence. Lymph node metastasis may be suggested only when coexisting recurrent mass is found in the proximal mesenteric root.",
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T1 - Significance of mesenteric lymphadenopathy after pancreaticoduodenectomy for periampullary carcinomas

T2 - Evaluation with serial MDCT studies

AU - Ishigami, Kousei

AU - Yoshimitsu, Kengo

AU - Irie, Hiroyuki

AU - Tajima, Tsuyoshi

AU - Asayama, Yoshiki

AU - Hirakawa, Masakazu

AU - Kakihara, Daisuke

AU - Shioyama, Yoshiyuki

AU - Nishihara, Yunosuke

AU - Yamaguchi, Koji

AU - Honda, Hiroshi

PY - 2007/3/1

Y1 - 2007/3/1

N2 - Objective: To evaluate the significance of mesenteric lymphadenopathy arising after pancreaticoduodenectomy (PD) for periampullary carcinomas. Materials and methods: Serial multidetector CT (MDCT) studies in 44 patients after PD for periampullary carcinomas (Group A) were retrospectively reviewed, the incidence and interval changes of mesenteric lymphadenopathy were evaluated, and comparisons were made with 21 patients who underwent PD for benign diseases (Group B). Results: In Group A, mesenteric lymphadenopathy was seen in 31 of 44 (70.5%) patients. The short axis diameter of the largest lymph node ranged from 6.2 to 11.5 mm (mean ± S.D.: 8.6 ± 1.4 mm), and the short-axis-to-long-axis (S/L) ratio ranged from 0.46 to 0.99 (mean ± S.D.: 0.69 ± 0.12). Six of the 31 (19.4%) mesenteric lymphadenopathy cases showed interval increases in size on follow-up studies, and three cases showed new development of mesenteric lymphadenopathy: all of these nine cases had concurrent recurrence in the mesenteric root. In Group B, 11 (52.4%) had mesenteric lymphadenopathy. The short axis diameter of the largest lymph node ranged from 5.6 to 10.9 mm (mean ± S.D.: 8.0 ± 1.9 mm) and the S/L ratio ranged from 0.48 to 0.93 (mean ± S.D.: 0.67 ± 0.12). Differences in the incidence, short axis diameter and S/L ratio were not significant between Groups A and B (p = 0.154, 0.271 and 0.654, respectively). Conclusion: Mesenetric lymphadenopathy after PD less likely reflects recurrence. Lymph node metastasis may be suggested only when coexisting recurrent mass is found in the proximal mesenteric root.

AB - Objective: To evaluate the significance of mesenteric lymphadenopathy arising after pancreaticoduodenectomy (PD) for periampullary carcinomas. Materials and methods: Serial multidetector CT (MDCT) studies in 44 patients after PD for periampullary carcinomas (Group A) were retrospectively reviewed, the incidence and interval changes of mesenteric lymphadenopathy were evaluated, and comparisons were made with 21 patients who underwent PD for benign diseases (Group B). Results: In Group A, mesenteric lymphadenopathy was seen in 31 of 44 (70.5%) patients. The short axis diameter of the largest lymph node ranged from 6.2 to 11.5 mm (mean ± S.D.: 8.6 ± 1.4 mm), and the short-axis-to-long-axis (S/L) ratio ranged from 0.46 to 0.99 (mean ± S.D.: 0.69 ± 0.12). Six of the 31 (19.4%) mesenteric lymphadenopathy cases showed interval increases in size on follow-up studies, and three cases showed new development of mesenteric lymphadenopathy: all of these nine cases had concurrent recurrence in the mesenteric root. In Group B, 11 (52.4%) had mesenteric lymphadenopathy. The short axis diameter of the largest lymph node ranged from 5.6 to 10.9 mm (mean ± S.D.: 8.0 ± 1.9 mm) and the S/L ratio ranged from 0.48 to 0.93 (mean ± S.D.: 0.67 ± 0.12). Differences in the incidence, short axis diameter and S/L ratio were not significant between Groups A and B (p = 0.154, 0.271 and 0.654, respectively). Conclusion: Mesenetric lymphadenopathy after PD less likely reflects recurrence. Lymph node metastasis may be suggested only when coexisting recurrent mass is found in the proximal mesenteric root.

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