Similar-case-based optimization of beam arrangements in stereotactic body radiotherapy for assisting treatment planners

Taiki Magome, Hidetaka Arimura, Yoshiyuki Shioyama, Katsumasa Nakamura, Hiroshi Honda, Hideki Hirata

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Objective. To develop a similar-case-based optimization method for beam arrangements in lung stereotactic body radiotherapy (SBRT) to assist treatment planners. Methods. First, cases that are similar to an objective case were automatically selected based on geometrical features related to a planning target volume (PTV) location, PTV shape, lung size, and spinal cord position. Second, initial beam arrangements were determined by registration of similar cases with the objective case using a linear registration technique. Finally, beam directions of the objective case were locally optimized based on the cost function, which takes into account the radiation absorption in normal tissues and organs at risk. The proposed method was evaluated with 10 test cases and a treatment planning database including 81 cases, by using 11 planning evaluation indices such as tumor control probability and normal tissue complication probability (NTCP). Results. The procedure for the local optimization of beam arrangements improved the quality of treatment plans with significant differences (P < 0.05) in the homogeneity index and conformity index for the PTV, V10, V20, mean dose, and NTCP for the lung. Conclusion. The proposed method could be usable as a computer-aided treatment planning tool for the determination of beam arrangements in SBRT.

Original languageEnglish
Article number309534
JournalBioMed Research International
Volume2013
DOIs
Publication statusPublished - Dec 4 2013

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Radiosurgery
Radiotherapy
Planning
Lung
Tissue
Organs at Risk
Therapeutics
Spinal Cord
Cost functions
Tumors
Databases
Costs and Cost Analysis
Radiation
Neoplasms

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)

Cite this

Similar-case-based optimization of beam arrangements in stereotactic body radiotherapy for assisting treatment planners. / Magome, Taiki; Arimura, Hidetaka; Shioyama, Yoshiyuki; Nakamura, Katsumasa; Honda, Hiroshi; Hirata, Hideki.

In: BioMed Research International, Vol. 2013, 309534, 04.12.2013.

Research output: Contribution to journalArticle

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AU - Honda, Hiroshi

AU - Hirata, Hideki

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